ID   A0A428TU59_9HYPO        Unreviewed;       477 AA.
AC   A0A428TU59;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Ribosomal lysine N-methyltransferase 4 {ECO:0000256|PIRNR:PIRNR011771};
DE            EC=2.1.1.- {ECO:0000256|PIRNR:PIRNR011771};
GN   ORFNames=CEP52_006120 {ECO:0000313|EMBL:RSM05597.1};
OS   Fusarium oligoseptatum.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Hypocreomycetidae; Hypocreales; Nectriaceae; Fusarium;
OC   Fusarium solani species complex.
OX   NCBI_TaxID=2604345 {ECO:0000313|EMBL:RSM05597.1, ECO:0000313|Proteomes:UP000287144};
RN   [1] {ECO:0000313|EMBL:RSM05597.1, ECO:0000313|Proteomes:UP000287144}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NRRL62579 {ECO:0000313|EMBL:RSM05597.1,
RC   ECO:0000313|Proteomes:UP000287144};
RA   Stajich J.E., Carrillo J., Kijimoto T., Eskalen A., O'Donnell K.,
RA   Kasson M.;
RT   "Comparative genomic analysis of Ambrosia Fusariam Clade fungi.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: S-adenosyl-L-methionine-dependent protein-lysine N-
CC       methyltransferase that monomethylates 60S ribosomal protein L42.
CC       {ECO:0000256|PIRNR:PIRNR011771}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PIRNR:PIRNR011771}.
CC   -!- SIMILARITY: Belongs to the class V-like SAM-binding methyltransferase
CC       superfamily. Histone-lysine methyltransferase family. SETD6 subfamily.
CC       {ECO:0000256|PIRNR:PIRNR011771}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM05597.1}.
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DR   EMBL; NKCK01000051; RSM05597.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428TU59; -.
DR   STRING; 1325735.A0A428TU59; -.
DR   Proteomes; UP000287144; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016279; F:protein-lysine N-methyltransferase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR   CDD; cd19178; SET_SETD6; 1.
DR   Gene3D; 3.90.1420.10; Rubisco LSMT, substrate-binding domain; 1.
DR   Gene3D; 3.90.1410.10; set domain protein methyltransferase, domain 1; 1.
DR   InterPro; IPR011383; N-lys_methylase_SETD6.
DR   InterPro; IPR015353; Rubisco_LSMT_subst-bd.
DR   InterPro; IPR036464; Rubisco_LSMT_subst-bd_sf.
DR   InterPro; IPR001214; SET_dom.
DR   InterPro; IPR046341; SET_dom_sf.
DR   InterPro; IPR044430; SETD6_SET.
DR   PANTHER; PTHR13271:SF34; N-LYSINE METHYLTRANSFERASE SETD6; 1.
DR   PANTHER; PTHR13271; UNCHARACTERIZED PUTATIVE METHYLTRANSFERASE; 1.
DR   Pfam; PF09273; Rubis-subs-bind; 1.
DR   Pfam; PF00856; SET; 1.
DR   PIRSF; PIRSF011771; RMS1_SET; 2.
DR   SUPFAM; SSF81822; RuBisCo LSMT C-terminal, substrate-binding domain; 1.
DR   SUPFAM; SSF82199; SET domain; 1.
DR   PROSITE; PS50280; SET; 1.
PE   3: Inferred from homology;
KW   Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW   ECO:0000256|PIRNR:PIRNR011771};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR011771};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287144};
KW   S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW   ECO:0000256|PIRNR:PIRNR011771};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PIRNR:PIRNR011771}.
FT   DOMAIN          27..272
FT                   /note="SET"
FT                   /evidence="ECO:0000259|PROSITE:PS50280"
SQ   SEQUENCE   477 AA;  54236 MW;  D667497B8022CA36 CRC64;
     MDSESFNAGS EKFLLWFKSL PGASFSDAIK IVDLRDRNAG RGIIALQDIP AETTLFTIPR
     KGIINVETSE LPKKLPDVFD LDKVIDDEDD EAPRLDSWSS LILIMIYEYL QGEKSPWKPY
     FDVLPSTFDT PMFWSESELD QLQASHMRYK IGKADAENMF RKTLLPIIRN NLGIFGGENR
     SDDDLVEIAH RMGSTIMAYA FDLENDEDEE EEEADGWVED REGKSMMGMV PMADILNADA
     EFNAHVNHEE ESLTVTSLRP IKAGEEIFNY YGPHPNSELL RRYGYVTERH SRYDVVEIPW
     DVVESVMRLN FGISGQVLER LRHDLEEEEE FEDTFVLERE TGEVNSDGTF SGPARFESMP
     EDLQQQLKTF LKGVKKAQPE AIPDKRKRDE IHHAVLAKTL QTLASKYPTS TSEDHILLQG
     QDLSQRTRMA IEVRLGEKKL LQEAIASTST VDVEMTIDDE SGPAKRAKTV GLRMNPS
//