ID   A0A428WCI8_9ACTN        Unreviewed;       410 AA.
AC   A0A428WCI8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=Integrase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=DMB66_56825 {ECO:0000313|EMBL:RSM40801.1};
OS   Actinoplanes sp. ATCC 53533.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM40801.1, ECO:0000313|Proteomes:UP000287606};
RN   [1] {ECO:0000313|EMBL:RSM40801.1, ECO:0000313|Proteomes:UP000287606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM40801.1,
RC   ECO:0000313|Proteomes:UP000287606};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM40801.1}.
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DR   EMBL; QHHV01000349; RSM40801.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428WCI8; -.
DR   OrthoDB; 3216232at2; -.
DR   Proteomes; UP000287606; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0015074; P:DNA integration; IEA:UniProtKB-KW.
DR   GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR   CDD; cd00397; DNA_BRE_C; 1.
DR   Gene3D; 1.10.150.130; -; 1.
DR   Gene3D; 1.10.443.10; Intergrase catalytic core; 1.
DR   InterPro; IPR044068; CB.
DR   InterPro; IPR011010; DNA_brk_join_enz.
DR   InterPro; IPR013762; Integrase-like_cat_sf.
DR   InterPro; IPR002104; Integrase_catalytic.
DR   InterPro; IPR010998; Integrase_recombinase_N.
DR   InterPro; IPR004107; Integrase_SAM-like_N.
DR   Pfam; PF02899; Phage_int_SAM_1; 1.
DR   Pfam; PF00589; Phage_integrase; 1.
DR   SUPFAM; SSF56349; DNA breaking-rejoining enzymes; 1.
DR   PROSITE; PS51900; CB; 1.
DR   PROSITE; PS51898; TYR_RECOMBINASE; 1.
PE   4: Predicted;
KW   DNA integration {ECO:0000256|ARBA:ARBA00022908};
KW   DNA recombination {ECO:0000256|ARBA:ARBA00023172};
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01248}; Reference proteome {ECO:0000313|Proteomes:UP000287606}.
FT   DOMAIN          40..153
FT                   /note="Core-binding (CB)"
FT                   /evidence="ECO:0000259|PROSITE:PS51900"
FT   DOMAIN          199..381
FT                   /note="Tyr recombinase"
FT                   /evidence="ECO:0000259|PROSITE:PS51898"
FT   REGION          159..185
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   410 AA;  45233 MW;  34527FFA7C1D709D CRC64;
     MEQNSAIAGR DLAGLVVTKA GRVVQTSDPT LPWVVLDGAG ARIDAADAFL KDLLACGSSA
     ASCRSYAFDL LRWFRFLAAV DVGWERASRA EVRDFVLWLR SSVNPARDRR RAGGPAPGSV
     NARTGKAHLR AGYAPATINH ALSVLAAFYE IHRASGSGPM VSPVPPQSRT GGRLDAHHNP
     LEPFRPHRRG IYRQKQPDRL PRAVPDDVID DVFTSLGSHR DRALVGMFLS SGARAAEMLG
     MTVADAHPGD GRIWVRTKGL GGIKQACPAS PEAFGWFALY LGEMADEGLR PGPDEPLWWT
     RRRPWRPLTY TALRALLNRV NDRIGANISW HDLRHTLCLR LIADPQVSLV DVQQVMRHRW
     ITTTGGYLRP QPDEVIAKVH EHYTRPKPAP QPLDGWDYDP QDLADVFGDA
//