ID A0A428WYA2_9ACTN Unreviewed; 483 AA.
AC A0A428WYA2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=FAD-containing monooxygenase EthA {ECO:0000313|EMBL:RSM48074.1};
GN ORFNames=DMB66_47015 {ECO:0000313|EMBL:RSM48074.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM48074.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM48074.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM48074.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974};
CC -!- SIMILARITY: Belongs to the FAD-binding monooxygenase family.
CC {ECO:0000256|ARBA:ARBA00010139}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM48074.1}.
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DR EMBL; QHHV01000201; RSM48074.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428WYA2; -.
DR OrthoDB; 5168853at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0004499; F:N,N-dimethylaniline monooxygenase activity; IEA:InterPro.
DR GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 3.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR020946; Flavin_mOase-like.
DR PANTHER; PTHR43872; MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED; 1.
DR PANTHER; PTHR43872:SF1; MONOOXYGENASE, PUTATIVE (AFU_ORTHOLOGUE AFUA_8G02570)-RELATED; 1.
DR Pfam; PF00743; FMO-like; 1.
DR Pfam; PF13450; NAD_binding_8; 1.
DR PRINTS; PR00411; PNDRDTASEI.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
PE 3: Inferred from homology;
KW FAD {ECO:0000256|ARBA:ARBA00022827};
KW Flavoprotein {ECO:0000256|ARBA:ARBA00022630};
KW Monooxygenase {ECO:0000313|EMBL:RSM48074.1};
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW Reference proteome {ECO:0000313|Proteomes:UP000287606}.
SQ SEQUENCE 483 AA; 53491 MW; 130846922218E0FB CRC64;
MAEHFDVLII GAGLSGIGAA WRLRQQRPGA SYAILEAREA IGGTWDLFRY PGVRSDSDMF
TLSYPFRPWQ GDRSLASGES ILRYIQDTAD EGGITPHIRF SARVVAADWA ADRWTVRLAG
GETLTCDFLY ACAGYYDYAK GHEPDFPGLG DFAGRFVHPQ SWPADLDHAG KRIIVIGSGA
TAVTLVPAMA ETAAHVTMLQ RSPSYLVALP GRDVVADQLR RRLPARVAYK LARAKNILLT
QGFYQLARRR PERVKAFLRR VAVRHLADPA GVDEHFTPAY QPWDQRLCIV PDGDLFEAIN
AGAASVVTDH IDRFVAEGIR LRSGRTLAAD VVVSATGLSL KLIGGVTLTV DGRAVDPGQR
VAYRGLMLSG VPNFAYCIGY TNASWTLRAD LSHRYVCRLL TYLDKNGFVS ATPRETPGNR
RPLLDLTSGY VQRALDSFPR QGDKDPWTVR QNYLLDVLTT PRADLRRDMT FTRRTAPVLE
EIR
//
