ID A0A428WZF4_9ACTN Unreviewed; 343 AA.
AC A0A428WZF4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RSM48445.1};
GN ORFNames=DMB66_46610 {ECO:0000313|EMBL:RSM48445.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM48445.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM48445.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM48445.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM48445.1}.
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DR EMBL; QHHV01000198; RSM48445.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428WZF4; -.
DR OrthoDB; 9785139at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd01574; PBP1_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000287606};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 13..67
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
SQ SEQUENCE 343 AA; 36667 MW; A60BD3F30DFA67CE CRC64;
MTPGRTRRPG RGVSMADVAR LAGVSSQTVS RVSTGHPGVV ESTRLQVLTA MQQLGYRPNS
AARALKRGEF RTLGVILFTL ATTGNSRTVE AIAGYAAKEG YAITLIPVAV PTQDGVLGAF
SRLGELAVDG IIVIMEVHLL DAANLNLPPG VQVVVVDSDA GDRYPVVDTD QADGARQAVR
HLLELGHETV WHVTGPAESF ASERRTQAWR RTLLEAGRAV PPVQRGDWSA ESGYRAGLAL
VAEPECTAVF AANDQMALGL LRAFHERGRT VPQDVSIVGF DDIPDAGSFI PPLTTVHQDF
AEVGRRCVQG LLRQIRNEPE GPGTVLVPTR LVLRASTAPP RRA
//
