ID A0A428X264_9ACTN Unreviewed; 649 AA.
AC A0A428X264;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 12.
DE SubName: Full=Helicase DnaB {ECO:0000313|EMBL:RSM49399.1};
GN ORFNames=DMB66_44850 {ECO:0000313|EMBL:RSM49399.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM49399.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM49399.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM49399.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Participates in initiation and elongation during chromosome
CC replication; it exhibits DNA-dependent ATPase activity.
CC {ECO:0000256|ARBA:ARBA00002835}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM49399.1}.
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DR EMBL; QHHV01000184; RSM49399.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428X264; -.
DR OrthoDB; 5150132at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR036185; DNA_heli_DnaB-like_N_sf.
DR InterPro; IPR007693; DNA_helicase_DnaB-like_N.
DR InterPro; IPR016136; DNA_helicase_N/primase_C.
DR InterPro; IPR025048; DUF3987.
DR PANTHER; PTHR30153:SF2; REPLICATIVE DNA HELICASE; 1.
DR PANTHER; PTHR30153; REPLICATIVE DNA HELICASE DNAB; 1.
DR Pfam; PF00772; DnaB; 1.
DR Pfam; PF13148; DUF3987; 1.
DR SUPFAM; SSF48024; N-terminal domain of DnaB helicase; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000313|EMBL:RSM49399.1};
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Helicase {ECO:0000313|EMBL:RSM49399.1};
KW Hydrolase {ECO:0000313|EMBL:RSM49399.1};
KW Nucleotide-binding {ECO:0000313|EMBL:RSM49399.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000287606}.
FT DOMAIN 7..104
FT /note="DNA helicase DnaB-like N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00772"
FT REGION 610..631
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 649 AA; 67965 MW; 0C2339598055B01F CRC64;
MSHAAFDLAA EQAVIGAALL APTLMADLAA TLAPSDFGRP AHTVLWESMC AMHAASIPTD
PITVTAHLAE AGDLGRVGGA PYLHTLTAEV PSAANAGHYA AIVASHAKRR KVADLGTQLA
QLAASGADAA EVLATGRALL DDADTPGGWS PLIPLGRGRH LPPFPAELLP GWLAEQVFAV
AEFTQTPIDA AGSIALACLS TAAGGRAEVE VRGSWREPTN LFTVVVLPPG SRKSAVFAAM
VSPILAAEKT LIERTAPAII EAELMAKVAG KAAEKAALAA ANANASGSDT LLAEATDAAM
KAESITVPVK PILVADDVTS ETATSWLAAQ GGRLAVLSPE GGIFATIAGR YSGTPNLEVF
LKGHAGDMLR VGRQSRDTEH IDKPALTMGL AVQPEILRDI AGMPGFRGLG LLARILFSLP
ENTVGFRTIG ADSIPTQVAA DYHARLHHLI LALAKQTDPI VLALTPEANE RVLDIERAVE
PRLRPGAAWA HIVDWGSKYT GAVIRIAGLL HLAENLPDGS GQYVSADTIE RAAMIGEYYA
AHALAAFDDM GADQSTRNAR QVLAWIERTT STAFTRRELF RAVQSTQLKT MADLDPVLAV
LEAHGYLRQL DPPAPKRAGG RPPSPSYLVH PDVHRPAATV HALDARRAA
//
