ID   A0A428X857_9ACTN        Unreviewed;       997 AA.
AC   A0A428X857;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 12.
DE   SubName: Full=XRE family transcriptional regulator {ECO:0000313|EMBL:RSM51494.1};
GN   ORFNames=DMB66_41770 {ECO:0000313|EMBL:RSM51494.1};
OS   Actinoplanes sp. ATCC 53533.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM51494.1, ECO:0000313|Proteomes:UP000287606};
RN   [1] {ECO:0000313|EMBL:RSM51494.1, ECO:0000313|Proteomes:UP000287606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM51494.1,
RC   ECO:0000313|Proteomes:UP000287606};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM51494.1}.
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DR   EMBL; QHHV01000158; RSM51494.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428X857; -.
DR   OrthoDB; 33864at2; -.
DR   Proteomes; UP000287606; Unassembled WGS sequence.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 2.
DR   InterPro; IPR041664; AAA_16.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR47691:SF3; HTH-TYPE TRANSCRIPTIONAL REGULATOR RV0890C-RELATED; 1.
DR   PANTHER; PTHR47691; REGULATOR-RELATED; 1.
DR   Pfam; PF13191; AAA_16; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF13424; TPR_12; 2.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00028; TPR; 5.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000287606}.
FT   DOMAIN          852..994
FT                   /note="Bacterial transcriptional activator"
FT                   /evidence="ECO:0000259|SMART:SM01043"
SQ   SEQUENCE   997 AA;  107036 MW;  D3239E8BB753EC83 CRC64;
     MTVGTAVTPP HTAVAPSAAG APLTRFVGRE AEIAALLAAA RRTRLLSLVG PGGSGKTRLA
     HVVRDRLAAT GGQPTWWVSL AQLDRPALLL SALADAVRAV EVPGQSLLEV IVGQLRERDG
     LLVLDNCEHL VAECAALAGE LLRACPALRI LTTSREPLAA AGETTWWLEG LSVPDDLPAP
     RAADLAGSQA VRLFTDRARL VLPGFAVTDA NAADLARLCR RLDGMPLALE LAAARLRVLP
     LPRIVGWLDD AVSLLVTTGR DVPARQATLR ATLDWSYDLL PAAERDLFAR LSVFRGGFTL
     AAAAAVAGDD AGVLDTLELL GRLVDKSLVQ ARTDGEEERY RLLEVVRQYA AEHLGDRAGT
     TAIRHACFML ELAERAEHGL AGGDLRLWLD GLHRDRNNIR AALSWSRHHN PGLGARLAGA
     LGRYWRLSGQ YAEGRQWLAA SVAATDGTTG PAARAKALTA LGTLEFLQCE YDQAVARLSQ
     AHRLYTRIGD DRGTAAALQS LASIAREQGR YAEARQHHRE VLAVGRRRGD PAAEARAIKS
     MGFTAWLEGD HLAAIESSTD AVRRFRELGD DEGLAGALVD LAAATFRRGD PDGAIPLLRQ
     SLAIADRLGL REATAWAQEQ LGLIAAARGE RAEAVRLLRH SLGVHHELGD RWRTACVLDA
     LAGQQDDPAG SARLLAAAAR LREMIGTPVP PCDLADHEQR SRAVHAALSP AQVERASMEG
     RALSVEQAVA AVLGGEPAVL GGEPAALAEA APAAEFVARA LGRGLVAVSG RELTPEDWTY
     AKPRELLFYL LTRPGSRKSE IGLALWPEAS GTELRNSFHT CLRFLRRALG DAARVRYAGG
     TYRVEPVLPL RYDVEDFRTA AAAARGHDGT PAAIGALTEA AARYPGDFLG DVPVGAWAEP
     HREELRREYE HVLRTLGGLL AKGRRFAEAA EVFARLVAHD PLLEAAHRGL MRCHAALGDR
     GRALRQYEHL VGLLEEQLGV PPSPETAELH ARLFPRR
//