ID   A0A428X876_9ACTN        Unreviewed;       332 AA.
AC   A0A428X876;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=NAD(P)-dependent alcohol dehydrogenase {ECO:0000313|EMBL:RSM51517.1};
GN   ORFNames=DMB66_41790 {ECO:0000313|EMBL:RSM51517.1};
OS   Actinoplanes sp. ATCC 53533.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM51517.1, ECO:0000313|Proteomes:UP000287606};
RN   [1] {ECO:0000313|EMBL:RSM51517.1, ECO:0000313|Proteomes:UP000287606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM51517.1,
RC   ECO:0000313|Proteomes:UP000287606};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM51517.1}.
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DR   EMBL; QHHV01000158; RSM51517.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428X876; -.
DR   OrthoDB; 3727682at2; -.
DR   Proteomes; UP000287606; Unassembled WGS sequence.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   CDD; cd08267; MDR1; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR020843; PKS_ER.
DR   PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR   PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR   Pfam; PF13602; ADH_zinc_N_2; 1.
DR   SMART; SM00829; PKS_ER; 1.
DR   SUPFAM; SSF50129; GroES-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000287606}.
FT   DOMAIN          10..321
FT                   /note="Enoyl reductase (ER)"
FT                   /evidence="ECO:0000259|SMART:SM00829"
SQ   SEQUENCE   332 AA;  35756 MW;  8FEB97B618DA0E05 CRC64;
     MKAVTYTRYG GPEVLRLADV PMPVPGDQDV LIRVRAAEAT KGDCELRSFR YSVKWFWLPL
     RVAVGISRPR RRILGMYFAG EVVSVGGRVT RFAPGDQVYG SAGLRQGAYG EYVALPDRAT
     IGPKPRTMTF AEAAAVPLGG LNALHFMRRA SIKPGEQVLI NGAGGSIGAH AVQIAHSMGA
     QVTAVDHGIK EDLVRALGAG DFLDYTTGDV TTTGRRFDVI FDMVPGSPYR RLVDMLNPGG
     RYLNGNPRLS VLARSVLTTR FTDKTVTVAF APETTEDLAT LTEMIEAGEI QSIVDRVYPM
     TEAAAAHRRV ETEQRLGAIV LTIGEPAGPT GP
//