ID A0A428XHS0_9ACTN Unreviewed; 342 AA.
AC A0A428XHS0;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RSM54840.1};
GN ORFNames=DMB66_36940 {ECO:0000313|EMBL:RSM54840.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM54840.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM54840.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM54840.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM54840.1}.
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DR EMBL; QHHV01000131; RSM54840.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428XHS0; -.
DR OrthoDB; 3510266at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR CDD; cd06267; PBP1_LacI_sugar_binding-like; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF138; HTH-TYPE TRANSCRIPTIONAL REGULATOR KDGR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000287606};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 8..61
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 312..342
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 342 AA; 35695 MW; D4CCA574B596234D CRC64;
MPRQQPRRTL QDLATTAGLS LAATSYALRG VRGSPATIRR VRELADEMGY TVNPIARALA
SGRTGSVGVS GSLRDLWQQD LSVLLTRSLR RQGQYATIAD ADGDPEQERL IVEQFAAQRI
DGAVVSPVDP TAGYWRLLGP QVAVVSIGDA LVGRPGSGSV LFDNRRGVQT ALAHLAGLGH
RRVGLLTPSL PSTPGRPAEV LAEQIAAGLE VELIAVAAPV ATTEAVATAA AMLADPGRPS
GVFCLSDSLA FAVYRAAREL GLRIPEDLSV VGYDDHQLAV LVSPGLTTLA WDEDAIVEAA
VSQLGGLLTG SASAPPPFRP ELIVRGSTTA PARSARSVPS PR
//
