ID A0A428XX25_9ACTN Unreviewed; 350 AA.
AC A0A428XX25;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE SubName: Full=LacI family transcriptional regulator {ECO:0000313|EMBL:RSM59824.1};
GN ORFNames=DMB66_26615 {ECO:0000313|EMBL:RSM59824.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM59824.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM59824.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM59824.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM59824.1}.
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DR EMBL; QHHV01000083; RSM59824.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428XX25; -.
DR OrthoDB; 128688at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd01392; HTH_LacI; 1.
DR Gene3D; 3.40.50.2300; -; 2.
DR Gene3D; 1.10.260.40; lambda repressor-like DNA-binding domains; 1.
DR InterPro; IPR000843; HTH_LacI.
DR InterPro; IPR046335; LacI/GalR-like_sensor.
DR InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR InterPro; IPR028082; Peripla_BP_I.
DR PANTHER; PTHR30146:SF121; HTH-TYPE TRANSCRIPTIONAL REPRESSOR CYTR; 1.
DR PANTHER; PTHR30146; LACI-RELATED TRANSCRIPTIONAL REPRESSOR; 1.
DR Pfam; PF00356; LacI; 1.
DR Pfam; PF13377; Peripla_BP_3; 1.
DR SMART; SM00354; HTH_LACI; 1.
DR SUPFAM; SSF47413; lambda repressor-like DNA-binding domains; 1.
DR SUPFAM; SSF53822; Periplasmic binding protein-like I; 1.
DR PROSITE; PS50932; HTH_LACI_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Reference proteome {ECO:0000313|Proteomes:UP000287606};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 23..78
FT /note="HTH lacI-type"
FT /evidence="ECO:0000259|PROSITE:PS50932"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 350 AA; 37213 MW; 1255A3565167C997 CRC64;
MSDGSQGRAP DGGHRGGDPS RPVTIAYIAE SAGVSVPTVS KVINGRSGVS ADTRARVEDL
VNRHKYRKPV AAHRSNVVEL VFRELESLWA VEIIRGVERV ARRHRAGVLV SNFGLHDSTV
PTAWDDTVAR RPHCVLSVAQ LSAAERAELT AKGIPFVVFD PTGELPDDVP FVGATNWSGG
RAATRHLLGL GHRRIAMISG PDHVLCCRAR QDGYRSAMEA AGLSAGPELL VHADLTREDG
CAAAARLLAR PERPTAIFAS NDLQALGVYQ AARKAGLRIP EDLSVVGFDD LPVVAWVEPP
LTTVHQPLTE MAVAATELAM SLGRGEQAPQ IGLEIATTLT VRNSTAPPSG
//
