ID   A0A428Y2U5_9ACTN        Unreviewed;       512 AA.
AC   A0A428Y2U5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=ABC-2 type transporter transmembrane domain-containing protein {ECO:0000259|Pfam:PF12698};
GN   ORFNames=DMB66_23840 {ECO:0000313|EMBL:RSM61895.1};
OS   Actinoplanes sp. ATCC 53533.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM61895.1, ECO:0000313|Proteomes:UP000287606};
RN   [1] {ECO:0000313|EMBL:RSM61895.1, ECO:0000313|Proteomes:UP000287606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM61895.1,
RC   ECO:0000313|Proteomes:UP000287606};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM61895.1}.
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DR   EMBL; QHHV01000069; RSM61895.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428Y2U5; -.
DR   OrthoDB; 185815at2; -.
DR   Proteomes; UP000287606; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0140359; F:ABC-type transporter activity; IEA:InterPro.
DR   Gene3D; 2.60.120.200; -; 1.
DR   InterPro; IPR013525; ABC2_TM.
DR   Pfam; PF12698; ABC2_membrane_3; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287606};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        305..325
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        346..372
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        392..415
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        422..441
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        486..507
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          301..505
FT                   /note="ABC-2 type transporter transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF12698"
FT   REGION          90..124
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          259..279
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   512 AA;  52334 MW;  236E829C5B947CFD CRC64;
     MRAVLHAEWT KLRTVRGWVV ALACAAAAVV GLGLLTGGQG SCGRNGPQPE CVLPVGPEGQ
     EVTDHFAFVH RSLTGDGSIT VRLNGLTGTL PAKPGMGGPD PADGTPQVAE RGPGDGRPGL
     APWAKGGLII KDGTRPGSTY AAIMMTGAHG VRMQHDYVHD KAGQPGPAST PRWLRLTRAG
     ETITGEESAD GTTWTVVDKV RLPGLPATVE AGTFATSPQF TWILGGGRGV SGAMGGPSEV
     TAAFDSLGQQ GTWSGATWTR STVGGDAEPS RPEQTSASFD VTGSGDIAPA VSGISGIGTT
     ISQTLAGTFA GLILVVVVAT MTMTAEYRRG LIRTTVAAVP RRARILLAKA AVIGAATFAL
     GVLAAAIVIF FGQQVLQASG VYLHPSTIGT QVRLVAGTGL LLAGAAVLAL ALGALLRRGL
     TAVVAGIVVI VLPYLLAMTV LPPEPAQWLL RVTPAAAFAV QQSAVSYPQV DDYPVPVNGY
     FPLPPWAGLA VLAGWAALAL GLAVLSLRRR DA
//