ID A0A428YMS9_9ACTN Unreviewed; 1162 AA.
AC A0A428YMS9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=OmpR/PhoB-type domain-containing protein {ECO:0000259|PROSITE:PS51755};
GN ORFNames=DMB66_10460 {ECO:0000313|EMBL:RSM69420.1};
OS Actinoplanes sp. ATCC 53533.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM69420.1, ECO:0000313|Proteomes:UP000287606};
RN [1] {ECO:0000313|EMBL:RSM69420.1, ECO:0000313|Proteomes:UP000287606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM69420.1,
RC ECO:0000313|Proteomes:UP000287606};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSM69420.1}.
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DR EMBL; QHHV01000028; RSM69420.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A428YMS9; -.
DR OrthoDB; 3208838at2; -.
DR Proteomes; UP000287606; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 2.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000287606}.
FT DOMAIN 1..99
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..99
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 255..278
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 262..276
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1162 AA; 124701 MW; 90825DCDDB9F48B6 CRC64;
MAAKNVEYRI LGPLAVCHDG RPVRISGAQQ RAVLAALLLR ANRMVSVERL VELLWGEEPP
GRARTLVHGC VARLRRDLRM PGDDSGPLLT QPPGYLLRVR PGELDLDRFT TLADGAGASG
DRAARLREAL ALWRGPALAD IQLPAIRAAA AGLDERMISV LEDRIDLDLR QGKLDGLVGE
LSALVHEHPL RERLWAQLML ARCAGRRPAE ALAAYRELRR KLIDQLGIEP SGRLRRMERA
ILADEDVWAV YRSGDSPAEA GRQPAPPDPP QLAPRPASPA LLGRSVEVAK LREALNDLAD
GSVLLGVAGD PGIGKTCLLA ELEQLARQDG RPVLAGRAAE FEKDAPFAVI KNALEDHLRT
VDPARLAGLA AGDRLLLTSI FPMIMIPAAG QQDSPATELI AAERYRLHRA FRALLDIVAR
PAGLVLILDD LHWCDDGSAE LLAHLLRHPP AAAVLLAFGY RPRQLDTRLH HEVLLARRRR
TGTVIEVGPL TFAEATALLP RALGADRRRQ LYTASEGNPF YLEFLARPPA PGDPGAPIGD
EVVPAAVGAA LAGEFAQLAA VEQRVAQAAA LVGDVLDSRL IAVVADLSEA DTLDAIDELG
RRDLIRRHRA SFKFRHPLLR SAAYQQAPAG WRVAAHRRAA DELARRGSPL AARARHVALA
AEPGDLDAVR LLEAAAAEAM HTTPAAAAHW CAAALRLLPQ RAQTVEMRLR LLNVQATALG
ITGHLARGRD ILNEILHLLP AGSEERIAVL GSLATLHQLL GNHVQAQVLL HGELARLPDQ
RGAPAAALRV SAVLCGVMSG SVAVDDIHTA IDVARGSGDR PLLASAVAIG AVASRSFDMA
GRRSPAEWAD EATRLVDAMP DADLARRLDA TLFLGWAESY LERFGPATRH ARRALGIARR
TGQGRLVGPL QMLIGVLDCM TGDLVSAAEA LDDALESAIL TGAREIRGRL LAYQAWVSVW
SGDVAGASES AAESVSLVEP AQATNWQAGQ AAGSLALVRF AAGDPDRCLE LMLQAGGGPG
LPAVRQVWQP MWLDTLSAAA TAAGRHQEAA EWADRAAMLP ADDTLSRRSA LILLAQVHPL
LHTRPERAVP LAQQAARLFD RAGDRLGAAR ARLHTASAFA GTGDAHRAEH EAERARLAFL
KCGARPDWLF RREHRPPRAE DG
//
