ID   A0A428YTY5_9ACTN        Unreviewed;       550 AA.
AC   A0A428YTY5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Alpha/beta hydrolase {ECO:0000313|EMBL:RSM73055.1};
GN   ORFNames=DMB66_03110 {ECO:0000313|EMBL:RSM73055.1};
OS   Actinoplanes sp. ATCC 53533.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1288362 {ECO:0000313|EMBL:RSM73055.1, ECO:0000313|Proteomes:UP000287606};
RN   [1] {ECO:0000313|EMBL:RSM73055.1, ECO:0000313|Proteomes:UP000287606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53533 {ECO:0000313|EMBL:RSM73055.1,
RC   ECO:0000313|Proteomes:UP000287606};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSM73055.1}.
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DR   EMBL; QHHV01000010; RSM73055.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A428YTY5; -.
DR   OrthoDB; 4006962at2; -.
DR   Proteomes; UP000287606; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR013595; Pept_S33_TAP-like_C.
DR   PANTHER; PTHR43248; 2-SUCCINYL-6-HYDROXY-2,4-CYCLOHEXADIENE-1-CARBOXYLATE SYNTHASE; 1.
DR   PANTHER; PTHR43248:SF29; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   Pfam; PF08386; Abhydrolase_4; 1.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:RSM73055.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287606};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..32
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           33..550
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5019307213"
FT   DOMAIN          88..245
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
FT   DOMAIN          412..515
FT                   /note="Peptidase S33 tripeptidyl aminopeptidase-like C-
FT                   terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08386"
SQ   SEQUENCE   550 AA;  58650 MW;  279FF11C80CB82AC CRC64;
     MTNRKQWRSR VALATAVTLA TTGILAGSPA RAAAPSAAPQ VAWSACEDGF ECATVPAPLD
     YDRPRGVQIA IALIRLPATD PARRIGSLLF NPGGPGGSGV EFARAVAHDL APEVRARFDI
     VGFDPRGINL STPLRCFDTF EQAVAVLPPF PYPDSPAEER QQRVSDDALA AACARHGGAI
     RDHMSSADAA RDMDLLRDRL GDEKLSYVGY SYGSLLGQNY ANLFPSRVRA LVIDGVVDPV
     AWSTGHGRDA RTVPVGGRIR SADGARRTLG EFFRLCDAAG AGCAFSGDAS RRYAALAKRL
     RGHPATITDP FTGETSTFTY NDLIAVTLGA LYDAHVWPDL AFFLDDVQRQ LSPAVLGQRL
     ATMRAKLGLA AQEEYPNAVE GSPGVACSDT DNPGSFAAWQ RSADRAEQRY GYFGRIWNWA
     WSVCRSWPAS AGQDRHLGPW TARTSAPVLV VGNYFDPATG YHGAQAAARL LPSSRLLTYA
     GWGHVAYFIA GNACVDTNVN QYLLNGRVPA AGTVCQPQGS PFGPATAAAQ RTTALSTVAV
     PAAVRRSFEP
//