ID A0A429BDA1_9ACTN Unreviewed; 981 AA.
AC A0A429BDA1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=HTH luxR-type domain-containing protein {ECO:0000259|PROSITE:PS50043};
GN ORFNames=DMB42_16355 {ECO:0000313|EMBL:RSN10479.1};
OS Nonomuraea sp. WAC 01424.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=2203200 {ECO:0000313|EMBL:RSN10479.1, ECO:0000313|Proteomes:UP000286861};
RN [1] {ECO:0000313|EMBL:RSN10479.1, ECO:0000313|Proteomes:UP000286861}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC 01424 {ECO:0000313|EMBL:RSN10479.1,
RC ECO:0000313|Proteomes:UP000286861};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSN10479.1}.
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DR EMBL; QHHZ01000005; RSN10479.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A429BDA1; -.
DR Proteomes; UP000286861; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd06170; LuxR_C_like; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR000792; Tscrpt_reg_LuxR_C.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR16305; TESTICULAR SOLUBLE ADENYLYL CYCLASE; 1.
DR PANTHER; PTHR16305:SF35; TRANSCRIPTIONAL ACTIVATOR DOMAIN; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF00196; GerE; 1.
DR PRINTS; PR00038; HTHLUXR.
DR SMART; SM00421; HTH_LUXR; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS00622; HTH_LUXR_1; 1.
DR PROSITE; PS50043; HTH_LUXR_2; 1.
PE 4: Predicted;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000286861}.
FT DOMAIN 895..960
FT /note="HTH luxR-type"
FT /evidence="ECO:0000259|PROSITE:PS50043"
FT REGION 103..125
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 981 AA; 103029 MW; F46A012206A38AF7 CRC64;
MILVDSFRGA RLWGVAMSSG QPLLHRDVET EAIREALSRV RAGGPSVLLI QGSRGMGKTT
LLNAALAARV ETGALLLMAR GHPTERDHPF GVVRRLFEPL MSAGRAPPTV PPGAGPGSAA
AGPDLGGDLG SDLGGGLDRG HPVTPDLLHG LYRATRSFTG DRPLIIAVDD VHHTDPQSSQ
WCSYIARRLD GLPIAMVLTT ADTGGPDDLA RDLAALPYTR LLRPAPLCAT CAGLLMESVL
GTEEPVGEDV ALACHRLTQG NPLLLRELAG RLARSGVRPV SAELPRVLEI GALALTETAL
GWLSGSGSGV DAAGVDLLRS LAIVAPEDGM EVASMIAGHG QDTARAAGET LRRAGLVTGT
PPDRFAHPRI QQAVLAGMDP GERDRLHRRT ASLLYRLGAP LRRSARHLMS AGPTGDPLTV
TVLREAAGEA AAKHSWEDAT GYLHRALAET DDPDTVLEVT AELGAVEKHR DLPACLRHLR
TVYGRVRLAP HALMSLAPFA DILVTANSAE AAEVFAGAAE TAAATPSLAG TDLLLVFAAQ
ALLWGRSAGR LGLRRLGRSL GTLVSPAARE FLSVLALATG ARGRSMSRML AQTRRCLDGQ
GAVPVAAVLP LVWGDRLDEA SYWAERLVSE TQDAGSGTGL ALALLTRAEV RYQLGSLEAG
LADAEAAVAS SRECQAEGFH VAAAACAARV LVEFGDLEAA ESALKSVAPY GDWHPMISGQ
ALDALGRVRL AQGRPRDGLL TLLECGRRLT AAGITNPACV PWGTNSILAY VLSGERSAAR
MVAERELELA RAWGAPTVVA RALSAGSIAH EGEVRLDMLH EAVALLANRG ARLEHARALL
RLGIAQRQAG DDGKAHETLA LALRLAADCG AVRLAALADK HRAATAPARA AGLVPGQDDH
VLTVGERRVT DLVLRGMSNL EVATTLSISK RTVDTHLARI YRKLGIHTRA ELAVILTGLS
DDDRADLRTG EPVPTGPHEF L
//
