ID   A0A429EB88_9ACTN        Unreviewed;       353 AA.
AC   A0A429EB88;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=Cyclase {ECO:0000313|EMBL:RSN46545.1};
GN   ORFNames=DMH08_35785 {ECO:0000313|EMBL:RSN46545.1};
OS   Actinomadura sp. WAC 06369.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2203193 {ECO:0000313|EMBL:RSN46545.1, ECO:0000313|Proteomes:UP000288610};
RN   [1] {ECO:0000313|EMBL:RSN46545.1, ECO:0000313|Proteomes:UP000288610}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC 06369 {ECO:0000313|EMBL:RSN46545.1,
RC   ECO:0000313|Proteomes:UP000288610};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSN46545.1}.
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DR   EMBL; QHJN01000219; RSN46545.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A429EB88; -.
DR   Proteomes; UP000288610; Unassembled WGS sequence.
DR   CDD; cd07817; SRPBCC_8; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR005031; COQ10_START.
DR   InterPro; IPR047137; ORF3.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   PANTHER; PTHR33824; POLYKETIDE CYCLASE/DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN; 1.
DR   PANTHER; PTHR33824:SF7; POLYKETIDE CYCLASE_DEHYDRASE AND LIPID TRANSPORT SUPERFAMILY PROTEIN; 1.
DR   Pfam; PF03364; Polyketide_cyc; 1.
DR   SUPFAM; SSF55961; Bet v1-like; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000288610}.
FT   DOMAIN          139..259
FT                   /note="Coenzyme Q-binding protein COQ10 START"
FT                   /evidence="ECO:0000259|Pfam:PF03364"
FT   REGION          48..68
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          294..353
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..324
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        325..347
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   353 AA;  38598 MW;  773B055ADA2AF586 CRC64;
     MAETKTKDAP GLIDDLPLDQ FKEASQDLAR AVMTRALASA NDRIRDLTGR LSESAGDGGG
     GGDGDGGGVG KKMLAAGAKE IAEGKSPLRA GMSAGMTGAK EKVKGVAGGL LGGGDGDGGG
     GGGSEKEAKV VNIVEEFDVG LPLRTTYDQW TRFGDYPSFT SKVESVEQES DEKLNWRAQI
     FLSHRSWKAT ITEQIPDTRI VWKSEGAKGY VDGAVTFAEL TPNLTRVLLV AEYHPDGFFE
     KTANLWRAQG RRLRLEFKHI KRHMMTRSVL EQDDIEGWRG EIRDGEVVKT HEDAVKEEQE
     AQENQDQEQS QEQDQDQEQD QEQDQDQEQG QKQDEGQEQE QDAEKVEAKS GAG
//