ID   A0A429F5H7_9ACTN        Unreviewed;       301 AA.
AC   A0A429F5H7;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=6-phosphogluconate dehydrogenase {ECO:0000313|EMBL:RSN56829.1};
GN   ORFNames=DMH08_24665 {ECO:0000313|EMBL:RSN56829.1};
OS   Actinomadura sp. WAC 06369.
OC   Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC   Thermomonosporaceae; Actinomadura.
OX   NCBI_TaxID=2203193 {ECO:0000313|EMBL:RSN56829.1, ECO:0000313|Proteomes:UP000288610};
RN   [1] {ECO:0000313|EMBL:RSN56829.1, ECO:0000313|Proteomes:UP000288610}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC 06369 {ECO:0000313|EMBL:RSN56829.1,
RC   ECO:0000313|Proteomes:UP000288610};
RA   Waglechner N., Wright G.D.;
RT   "Evolution of GPA BGCs.";
RL   Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the HIBADH-related family.
CC       {ECO:0000256|ARBA:ARBA00009080}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSN56829.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; QHJN01000098; RSN56829.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A429F5H7; -.
DR   Proteomes; UP000288610; Unassembled WGS sequence.
DR   GO; GO:0050661; F:NADP binding; IEA:InterPro.
DR   GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013328; 6PGD_dom2.
DR   InterPro; IPR006115; 6PGDH_NADP-bd.
DR   InterPro; IPR015815; HIBADH-related.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR048666; RedAm-like_C.
DR   PANTHER; PTHR43580; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   PANTHER; PTHR43580:SF2; OXIDOREDUCTASE GLYR1-RELATED; 1.
DR   Pfam; PF03446; NAD_binding_2; 1.
DR   Pfam; PF21761; RedAm-like_C; 1.
DR   PIRSF; PIRSF000103; HIBADH; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000288610}.
FT   DOMAIN          22..168
FT                   /note="6-phosphogluconate dehydrogenase NADP-binding"
FT                   /evidence="ECO:0000259|Pfam:PF03446"
FT   DOMAIN          173..298
FT                   /note="NADPH-dependent reductive aminase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF21761"
SQ   SEQUENCE   301 AA;  31088 MW;  3924D634CE670F8E CRC64;
     MTDAHTDELA NELANESALE SVTVIGLGLM GRALASALLA AGHPTTVWNR TAAKADDLVA
     RGATLAPTVG DAVRDGSLII VCLADADAVR EAVGPHRAGL AGRTLVNLTS GTAEEAREIA
     GWTADRLDGA IMATPEVIGR PEAFLLYSGS PDAFEKHRET LGRLGSATFF GADPGLASLY
     DVALLGIMWG TLNAFLHGSA LLGAAGVKAS DFAPFAVQWV SSVSGFATAY AAQIDRGGYP
     AEDASLDTHI ATMKYLVRES AAAGIDTDWP ARIQALAERA VQAGHAGASY ASLIEVFRGR
     A
//