ID A0A429GEA9_9ACTN Unreviewed; 1080 AA.
AC A0A429GEA9;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE SubName: Full=Transcriptional regulator {ECO:0000313|EMBL:RSN72177.1};
GN ORFNames=DMH08_00530 {ECO:0000313|EMBL:RSN72177.1};
OS Actinomadura sp. WAC 06369.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Thermomonosporaceae; Actinomadura.
OX NCBI_TaxID=2203193 {ECO:0000313|EMBL:RSN72177.1, ECO:0000313|Proteomes:UP000288610};
RN [1] {ECO:0000313|EMBL:RSN72177.1, ECO:0000313|Proteomes:UP000288610}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=WAC 06369 {ECO:0000313|EMBL:RSN72177.1,
RC ECO:0000313|Proteomes:UP000288610};
RA Waglechner N., Wright G.D.;
RT "Evolution of GPA BGCs.";
RL Submitted (MAY-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC {ECO:0000256|ARBA:ARBA00005820}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSN72177.1}.
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DR EMBL; QHJN01000001; RSN72177.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A429GEA9; -.
DR Proteomes; UP000288610; Unassembled WGS sequence.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0000160; P:phosphorelay signal transduction system; IEA:InterPro.
DR GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR CDD; cd15831; BTAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR005158; BTAD.
DR InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF03704; BTAD; 1.
DR Pfam; PF00486; Trans_reg_C; 1.
DR SMART; SM01043; BTAD; 1.
DR SMART; SM00862; Trans_reg_C; 1.
DR SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS51755; OMPR_PHOB; 1.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000288610}.
FT DOMAIN 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000259|PROSITE:PS51755"
FT DNA_BIND 1..98
FT /note="OmpR/PhoB-type"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
FT REGION 252..279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 254..278
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1080 AA; 114043 MW; 859A59AE7E3E2004 CRC64;
MVFIRVLGSF AAEVHGESVH LGGPRQRGVL ALLAAARGRV VPVDRMIEDL WRGEPPARAL
TSLQAYVSNL RRLLEPARPP RTPARLLVSA PPGYALRLPP ESVDAWRFED LLDRARADPD
PRAARARLAE ALALWRGPAF AEVADEPWAA AETARLNELR LVAAELHVAA GLRTGDPAAV
VPQAERLTRE EPLREEGWRL HALALWSSGR QADALAALRR ARGVFAEELG LDPGPDLTAL
EEAILTRRTD VMRETVPPPP PPPPSPPPPA PPPAPVGEAP FVGREAELSA LVTAATEAAG
DGARVALVTG EAGLGKSTLL EHLGGRLERD GWLVAAGHCP EVDGAPPAWA WTEALRAVAA
AAPPGAFAAD LAPLLTDTGP VAADAAAGRF RLRRAVWRWL AAVASERPVA VVLDDLHRAD
AATLELLGGG LGLRAPILVV AAYRADESAH LTDTLASLAR AAPLRLPLRG LDGEAVAELV
RSECETDEET VAGIAERTGG NPFYVRESAR LLNGEGALVA LSEVPEGVRD VLRRRFARLP
EGGVAVLRLA AVAGRESSVE VLVNAADTDE DGVLDALDAG VIAGLLSEPG PGRVRFVHAL
VRDTLVADVS RLRAARMHAR IAAALEGTGD VAALAHHYAR AGSPKAVRYC VEAADLAEAR
YAHDVAADLL TAALANASDP RERVDLHGRL LRSQIRAGAV GAARETRREA VEYAESLGRD
DLMIAAFTAW TEPTPWQSRP YGTVDRPVVD RLSRLLERTD LAPETRGRLL VAYADELAGE
DDPTVLAAAR EALGLAAGPH LRAAALGVLA RGIGGPDGRA GLCRDLVAIG VEHGVPAYRV
AGLLNHACAA AEANDPATMR RTAAEAGGLA RAYRLPEAAG VAEVTLATLA LIEGRSADAE
RRYRRAADGM RRAGSLHASG FLGFALAATW MSDGTLVTRL DEVRALHEAA GPMASDLLVL
ALHGNGLSGE ARRVRTSAPI RPDYFFTFLT TLRAMAAMVL DDRAAAEETY ARLLPHRGGP
PAGAASLSLA LRPVAHTLGE LALFLGRDRR AAAHFAEAAA IADRWNAPHW AADARSRIPA
//
