ID   A0A429NB87_9ACTN        Unreviewed;       911 AA.
AC   A0A429NB87;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=GAF domain-containing protein {ECO:0000313|EMBL:RSS03902.1};
GN   ORFNames=EF917_12435 {ECO:0000313|EMBL:RSS03902.1};
OS   Streptomyces sp. WAC00469.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2487415 {ECO:0000313|EMBL:RSS03902.1, ECO:0000313|Proteomes:UP000269080};
RN   [1] {ECO:0000313|EMBL:RSS03902.1, ECO:0000313|Proteomes:UP000269080}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC00469 {ECO:0000313|EMBL:RSS03902.1,
RC   ECO:0000313|Proteomes:UP000269080};
RA   Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT   "Unmasking the antibiotic production potential of Actinomycetes through
RT   CRISPR/Cas9 inactivation of ubiquitous gene clusters.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSS03902.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; RPRX01000032; RSS03902.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A429NB87; -.
DR   OrthoDB; 9807247at2; -.
DR   Proteomes; UP000269080; Unassembled WGS sequence.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd16936; HATPase_RsbW-like; 1.
DR   CDD; cd00130; PAS; 1.
DR   Gene3D; 3.30.450.40; -; 2.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.450.20; PAS domain; 1.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR003594; HATPase_C.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR000014; PAS.
DR   InterPro; IPR035965; PAS-like_dom_sf.
DR   InterPro; IPR013767; PAS_fold.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   NCBIfam; TIGR00229; sensory_box; 1.
DR   PANTHER; PTHR43156:SF2; MULTIDOMAIN REGULATORY PROTEIN RV1364C; 1.
DR   PANTHER; PTHR43156; STAGE II SPORULATION PROTEIN E-RELATED; 1.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF13492; GAF_3; 1.
DR   Pfam; PF13581; HATPase_c_2; 1.
DR   Pfam; PF00989; PAS; 1.
DR   Pfam; PF07228; SpoIIE; 1.
DR   SMART; SM00065; GAF; 2.
DR   SMART; SM00091; PAS; 1.
DR   SMART; SM00331; PP2C_SIG; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF55781; GAF domain-like; 2.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR   PROSITE; PS50112; PAS; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000269080}.
FT   DOMAIN          201..231
FT                   /note="PAS"
FT                   /evidence="ECO:0000259|PROSITE:PS50112"
FT   REGION          1..37
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   911 AA;  96824 MW;  5329006F38DAA319 CRC64;
     MTTGVIGGQP LQPRASGAPL SAQHHAPLGP HGDVDNRTRS SVITARAAAS FEPLGRSVAT
     ARSFVRDTLH GWGFADVVDD AVVLTSELVT NAVVHAGTAA EVVCLRSDHG VRIEVSDRYP
     EREVPVQSAP VIMGSPDQEG GRGLQLCAAL AGRWGVEYTP THKTVWFQLD LPERPVGTRS
     AGPVLPTELL PATEGRVRVA VVQVDRNGTV TAWNEDAEAL FGYAADQVVG KPLTDLAAWP
     HTPGTGTGIA EALQLSRWEG SYGIRGVHGR VIPVYGSHLR VRDTSGEPST VCLLVRDHER
     AVLQTPLRAT GDTGTSSDSA TADPFEVFIG SPAPDDLDTL LQRTVERARD MLDGDAAFLL
     LATDDETELE VRATTGLPSA RQRFARVPVE AGPGRYGSAR MPAVHDDLTA VPGAVPLLRG
     TGMRSLVTVP LKVEGRLTGS LGVAAEAPGR YSNEEALRLQ FAADRIALAV ESARLGELER
     LRRGSLSFLV EASDLLAGTL DRDQTLALMA QMTVPTLATW CAVYTIADQA SEPFLSYVLH
     EDEELIDGIK SLLSKIPPPD PVPTPGARVW TAPGEAAHQA ALRSSMRSLG LGDSHHQVGT
     SIGPTLATAA AVGGETVVLP LVARNRVIGM LTLGKPTDEH FRQEILELAE DLSRRAALAL
     DNARLYSERT AISQSLQRSL LPPGLPQIDG VEVDVIYRAA GEGNEVGGDF YDLFPIRDGA
     YGFAIGDVCG TGPEAAAVTG LARHALRLLA REGYDGPSVL QRLNSAILDE GARSRFLTLL
     YGELRPQENG SAELKVVCAG HPLPLRLRQD GTVEPAAEPQ PLLGVIEDLE LYEQTVVLDP
     GDVLLCVTDG VTERREGTRM LGDDGLADVL TTCTGLTAGA VAARIMRAVE RFAQDAPSDD
     MAILAMRVPE N
//