ID   A0A429RXX6_9ACTN        Unreviewed;       356 AA.
AC   A0A429RXX6;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 10.
DE   SubName: Full=GTP-binding protein {ECO:0000313|EMBL:RSS78812.1};
GN   ORFNames=EF918_19605 {ECO:0000313|EMBL:RSS78812.1};
OS   Streptomyces sp. WAC06614.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=2487416 {ECO:0000313|EMBL:RSS78812.1, ECO:0000313|Proteomes:UP000277644};
RN   [1] {ECO:0000313|EMBL:RSS78812.1, ECO:0000313|Proteomes:UP000277644}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WAC06614 {ECO:0000313|EMBL:RSS78812.1,
RC   ECO:0000313|Proteomes:UP000277644};
RA   Culp E., Yim G., Waglechner N., Wang W., Pawlowski A.C., Wright G.D.;
RT   "Unmasking the antibiotic production potential of Actinomycetes through
RT   CRISPR/Cas9 inactivate of ubiquitous gene clusters.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=GTP + H2O = GDP + H(+) + phosphate; Xref=Rhea:RHEA:19669,
CC         ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:37565,
CC         ChEBI:CHEBI:43474, ChEBI:CHEBI:58189;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC       PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:19670;
CC         Evidence={ECO:0000256|ARBA:ARBA00001702};
CC   -!- SIMILARITY: Belongs to the SIMIBI class G3E GTPase family. ZNG1
CC       subfamily. {ECO:0000256|ARBA:ARBA00034320}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSS78812.1}.
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DR   EMBL; RPRY01000139; RSS78812.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A429RXX6; -.
DR   OrthoDB; 9808822at2; -.
DR   Proteomes; UP000277644; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   CDD; cd03112; CobW-like; 1.
DR   Gene3D; 3.30.1220.10; CobW-like, C-terminal domain; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR036627; CobW-likC_sf.
DR   InterPro; IPR011629; CobW-like_C.
DR   InterPro; IPR003495; CobW/HypB/UreG_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR13748; COBW-RELATED; 1.
DR   PANTHER; PTHR13748:SF70; PROTEIN COBW; 1.
DR   Pfam; PF02492; cobW; 1.
DR   Pfam; PF07683; CobW_C; 1.
DR   SMART; SM00833; CobW_C; 1.
DR   SUPFAM; SSF90002; Hypothetical protein YjiA, C-terminal domain; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277644}.
FT   DOMAIN          237..328
FT                   /note="CobW C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00833"
SQ   SEQUENCE   356 AA;  38730 MW;  AF8A0C7437845BC9 CRC64;
     MNSRQPLPVV VLAGFLGSGK TTLLNHLLRS SRGTRIGVVV NDFGAIEIDA MSVAGQVGDS
     MVSLGNGCLC CAVDGSELDA YLEKLSRPQH RIDVIVIEAS GLAEPQEMIR MLVANEDPAV
     HYGGLVQVVD AAEFDATRAR HPETDRHLAL ADLVVLNKAD RVDAAALARV EEVIHGLCPG
     TPVVTADHGR IDPDLLFDRK EWTETRGQLS FEDLIAEAEA AAGTSEEDHS GHAHTHYEST
     EFVSEQALSP RRFVDFLDRR PHGLYRIKGY VHFGVPGHDE KYEIHAVGRF LRFTPLPWAR
     GEPRLTQLVM IGSGTDGPAL LAGLEACREP APHTLDPASM WGVLRYVAHP RTEPAG
//