ID A0A430AIG7_9ENTE Unreviewed; 617 AA.
AC A0A430AIG7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Cell division protein FtsI {ECO:0000313|EMBL:RSU07828.1};
GN ORFNames=CBF30_00890 {ECO:0000313|EMBL:RSU07828.1};
OS Vagococcus entomophilus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Vagococcus.
OX NCBI_TaxID=1160095 {ECO:0000313|EMBL:RSU07828.1, ECO:0000313|Proteomes:UP000288669};
RN [1] {ECO:0000313|EMBL:RSU07828.1, ECO:0000313|Proteomes:UP000288669}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 24756 {ECO:0000313|EMBL:RSU07828.1,
RC ECO:0000313|Proteomes:UP000288669};
RA Gulvik C.A.;
RT "Vagococcus spp. assemblies.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004162};
CC Single-pass membrane protein {ECO:0000256|ARBA:ARBA00004162}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the transpeptidase family.
CC {ECO:0000256|ARBA:ARBA00007171}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSU07828.1}.
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DR EMBL; NGJZ01000001; RSU07828.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A430AIG7; -.
DR OrthoDB; 9804124at2; -.
DR Proteomes; UP000288669; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0008658; F:penicillin binding; IEA:InterPro.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 2.20.70.70; -; 1.
DR Gene3D; 3.30.70.2110; -; 1.
DR Gene3D; 3.40.710.10; DD-peptidase/beta-lactamase superfamily; 1.
DR Gene3D; 3.90.1310.10; Penicillin-binding protein 2a (Domain 2); 1.
DR InterPro; IPR012338; Beta-lactam/transpept-like.
DR InterPro; IPR005311; PBP_dimer.
DR InterPro; IPR036138; PBP_dimer_sf.
DR InterPro; IPR001460; PCN-bd_Tpept.
DR PANTHER; PTHR30627; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE; 1.
DR PANTHER; PTHR30627:SF1; PEPTIDOGLYCAN D,D-TRANSPEPTIDASE FTSI; 1.
DR Pfam; PF03717; PBP_dimer; 1.
DR Pfam; PF00905; Transpeptidase; 1.
DR SUPFAM; SSF56601; beta-lactamase/transpeptidase-like; 1.
DR SUPFAM; SSF56519; Penicillin binding protein dimerisation domain; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000313|EMBL:RSU07828.1};
KW Cell division {ECO:0000313|EMBL:RSU07828.1};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000288669};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 24..43
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 71..251
FT /note="Penicillin-binding protein dimerisation"
FT /evidence="ECO:0000259|Pfam:PF03717"
FT DOMAIN 294..594
FT /note="Penicillin-binding protein transpeptidase"
FT /evidence="ECO:0000259|Pfam:PF00905"
SQ SEQUENCE 617 AA; 67108 MW; 80019134577DA846 CRC64;
MNMDQFKKYL ASKNLNPKNN RKRVGVILFA VAIGIFSIFA LRLSSIIVTG RVGNVSLAEK
TKELYEGSSV IKAKRGSILD RNGNPIAEDA TSYSLYAMLD KNYIGIGKKE LYVHDKDREK
IAEVLNQYTG MDKDYALGQL QPKKNSQGKE ITTVEFGTSG KGLTLETKSK IEKALKKEGI
TGIFFNEHPA RSYPNGNFAS YLVGYTQFAD ASDDTKGLKG MLGIEEAYNS QLSGSDGEIT
YQKDSGGNAV PGTQTVKKKA KNGSDIYTTL DSNLQLYLEE LMDGVDSKYQ PESMTAMLVE
AKTGDVVAAS QRPTFNPETK DGLGTNGVWQ NLLVQDTFEP GSTMKVFTVA TAIEAGVFNP
NTTFLSGKIK VDDTTISDWI PAGKGYLTYP QALAWSSNVG MVHLEQLMPT AWQEYIKKFG
FTKSTHSGLV SNEPTGSVQN STTVDRAMTA YGQAIAVTDF QMIQGFTAIA NNGKMLKPQY
ISKITTADGK TTTKKTKVVS QPISSQTAKQ VLGYMQGVVD DKTYGTGYGI YNIDGYNVSA
KTGTAQIFEN GHYSDDGYIN SVVQIAPTEN PKYIMYVTIK RPKVPEGGST SDALSSISNP
LLKRALDLDT GKTTSSK
//
