ID A0A430ALM4_9ENTE Unreviewed; 725 AA.
AC A0A430ALM4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 11.
DE RecName: Full=HD/PDEase domain-containing protein {ECO:0000259|SMART:SM00471};
GN ORFNames=CBF29_12485 {ECO:0000313|EMBL:RSU09021.1};
OS Vagococcus elongatus.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Enterococcaceae; Vagococcus.
OX NCBI_TaxID=180344 {ECO:0000313|EMBL:RSU09021.1, ECO:0000313|Proteomes:UP000287605};
RN [1] {ECO:0000313|EMBL:RSU09021.1, ECO:0000313|Proteomes:UP000287605}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CCUG 51432 {ECO:0000313|EMBL:RSU09021.1,
RC ECO:0000313|Proteomes:UP000287605};
RA Gulvik C.A.;
RT "Vagococcus spp. assemblies.";
RL Submitted (MAY-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSU09021.1}.
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DR EMBL; NGKA01000027; RSU09021.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A430ALM4; -.
DR OrthoDB; 9806952at2; -.
DR Proteomes; UP000287605; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00077; HDc; 1.
DR Gene3D; 1.10.3210.10; Hypothetical protein af1432; 1.
DR InterPro; IPR003607; HD/PDEase_dom.
DR InterPro; IPR006674; HD_domain.
DR InterPro; IPR006675; HDIG_dom.
DR InterPro; IPR011624; Metal-dep_PHydrolase_7TM_extra.
DR InterPro; IPR011621; Metal-dep_PHydrolase_7TM_intra.
DR NCBIfam; TIGR00277; HDIG; 1.
DR PANTHER; PTHR36442; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR PANTHER; PTHR36442:SF1; CYCLIC-DI-AMP PHOSPHODIESTERASE PGPH; 1.
DR Pfam; PF07698; 7TM-7TMR_HD; 1.
DR Pfam; PF07697; 7TMR-HDED; 1.
DR Pfam; PF01966; HD; 1.
DR SMART; SM00471; HDc; 1.
DR SUPFAM; SSF109604; HD-domain/PDEase-like; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000287605};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..32
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 287..309
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 321..341
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 347..365
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 424..442
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 454..477
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 506..662
FT /note="HD/PDEase"
FT /evidence="ECO:0000259|SMART:SM00471"
SQ SEQUENCE 725 AA; 82107 MW; F6D86FBD962F62B0 CRC64;
MKFDFKSLID KFGRRYIIII TALFALILGL LMSGSVKQTN RDLKEGKLAE ETIRANKTIE
NKDETEERKK LAAEAMPPTY SFDDSVAKHR VELTTQLFSY IEATNKELQE KYQADLERAK
ERNSVEAPTV EDKIANLKGR LEKIDSDDIN FFQDISQGFY QGVFELPEDE FNLLKTEMLN
IVEKTMGERI RDNNLAEHRA SAKESIGASL LSEDGKNLAE DLIDKVVVVN EVFDEKATAA
AKETAKEAVN PVMIYHGEVI VREGAQIDSR AIKKLELLGM TNKNNTIFPY VAMIMLIVIQ
LGLLVWLVMR EGTKEFQFRF INFYVFMMVL SILFMKAIAL FQTESMPYIS LLFPAAFTPL
VLNLFISRKA SVLAALFQVA FSVFVFYDLG GTSTLILLLM SYLFSGLMAS LIKQERIGRQ
LGRALIMLII VPLAFTIVMS TYQGMDFGDR KTVSAILCML IGSLFTYVLS IGLHPYIELL
LNDDSMIVLN ELSNPNHPLL KRLLEEAPGT YHHSMMVASL SSNAVAAIGG RSLITRVACY
YHDIGKLKHA NFFVENLPSG AENPHNFLLP EDSKEIIFSH VSEGVKILKK QKMPKMIVDI
CEQHHGTTLM SFFYIKAYER DKNVKEEDFR YPGPRPQTKE AAVVNLADTC EAAVRAMKQP
TNETIHEFVH DLVEKRIKDN QLDESGLTLG EIRIIEKSII NGLCSAYHSR IEYPKMKKEI
EENNK
//
