ID   A0A430BD94_9SPHN        Unreviewed;       603 AA.
AC   A0A430BD94;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 14.
DE   SubName: Full=Chloride channel protein {ECO:0000313|EMBL:RSU46714.1};
GN   ORFNames=BRX43_15190 {ECO:0000313|EMBL:RSU46714.1};
OS   Sphingomonas sp. S-NIH.Pt15_0812.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=1920129 {ECO:0000313|EMBL:RSU46714.1, ECO:0000313|Proteomes:UP000287772};
RN   [1] {ECO:0000313|EMBL:RSU46714.1, ECO:0000313|Proteomes:UP000287772}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=S-NIH.Pt15_0812 {ECO:0000313|EMBL:RSU46714.1,
RC   ECO:0000313|Proteomes:UP000287772};
RA   Johnson R.C., Deming C., Conlan S., Zellmer C., Michelin A., Lee-Lin S.-Q.,
RA   Thomas P.J., Park M., Weingarten R.A., Less J., Dekker J.P., Frank K.M.,
RA   Musser K.A., Mcquiston J.R., Henderson D.K., Lau A.F., Palmore T.N.,
RA   Segre J.A.;
RT   "Genomic and Epidemiologic Investigation to Identify Sphingomonas koreensis
RT   Point Sources in an Indolent Hospital Outbreak.";
RL   Submitted (JUN-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RSU46714.1}.
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DR   EMBL; QLJH01000026; RSU46714.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A430BD94; -.
DR   OrthoDB; 9814803at2; -.
DR   Proteomes; UP000287772; Unassembled WGS sequence.
DR   GO; GO:0034707; C:chloride channel complex; IEA:UniProtKB-KW.
DR   GO; GO:0005247; F:voltage-gated chloride channel activity; IEA:InterPro.
DR   CDD; cd00400; Voltage_gated_ClC; 1.
DR   Gene3D; 3.10.580.10; CBS-domain; 1.
DR   Gene3D; 1.10.3080.10; Clc chloride channel; 1.
DR   InterPro; IPR000644; CBS_dom.
DR   InterPro; IPR046342; CBS_dom_sf.
DR   InterPro; IPR014743; Cl-channel_core.
DR   InterPro; IPR001807; Cl-channel_volt-gated.
DR   PANTHER; PTHR43427; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   PANTHER; PTHR43427:SF6; CHLORIDE CHANNEL PROTEIN CLC-E; 1.
DR   Pfam; PF00571; CBS; 1.
DR   Pfam; PF00654; Voltage_CLC; 1.
DR   SUPFAM; SSF54631; CBS-domain pair; 1.
DR   SUPFAM; SSF81340; Clc chloride channel; 1.
DR   PROSITE; PS51371; CBS; 1.
PE   4: Predicted;
KW   CBS domain {ECO:0000256|PROSITE-ProRule:PRU00703};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000287772};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        45..71
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        91..109
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        187..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        258..278
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        298..318
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        330..353
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        359..381
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        393..416
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        422..443
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          537..595
FT                   /note="CBS"
FT                   /evidence="ECO:0000259|PROSITE:PS51371"
SQ   SEQUENCE   603 AA;  63139 MW;  CB19B1E18CBE2461 CRC64;
     MAGTRRHDFD PTSSARRGAR VSIGAPSHWA ARLHAFGTRV RATELLFVLV AVAIGMGAGL
     LTVLQGALAR TVQHLLYRMP GPTRLSGMPQ LAWWQLLILP VGGCVLVGFN RLVGTQRRAL
     VDTVEANALH GGVLSGRDSA IVSGQTILSN GFGASVGLEA AYAQLGGLIA SLAGRWLRLR
     RIDIRTLVGA GAGGAIAAAF GAPLAGAFYA FEVVIGAYTP ATIAPVVAAS LAGAQVARRL
     GVVPYIVDVD RGPAIQTFGY LVYGSLGVLC AAIGIALMRL VGATEARTRA HLPGWSRPIV
     GGMLLAGLAA ISPQVLSAGH SALHIDLVQA LPLAVVATLL ATKALASIVS LGFGFRGGLF
     FASLFLGTLV GHFYADALAA IAGVEVLDAG NAAMVGMAAL AVAVIGAPFT MTMLVLEATG
     NFSLTGAVLA ASLVSSTIVR QFFGYSFSTW RLHLRGETIR SLRDVGWVKS LTAGRMMRRQ
     PNMIAGSATV AEFRRRFPLG ATKRVILLDA TDHYAGIVDP VAVHDGAVGA DRPVIDLAQG
     RDQVLRPDMD IRAVMALFDA TRREELAVVD DQGAVLGLVT EAHVRRRYGE EVEKSQRELF
     GEA
//