ID A0A430FTZ2_9BIFI Unreviewed; 867 AA.
AC A0A430FTZ2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=D2E24_1079 {ECO:0000313|EMBL:RSX56534.1};
OS Bifidobacterium samirii.
OC Bacteria; Actinomycetota; Actinomycetes; Bifidobacteriales;
OC Bifidobacteriaceae; Bifidobacterium.
OX NCBI_TaxID=2306974 {ECO:0000313|EMBL:RSX56534.1, ECO:0000313|Proteomes:UP000287470};
RN [1] {ECO:0000313|EMBL:RSX56534.1, ECO:0000313|Proteomes:UP000287470}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2033B {ECO:0000313|EMBL:RSX56534.1,
RC ECO:0000313|Proteomes:UP000287470};
RA Lugli G.A., Duranti S., Milani C.;
RT "Characterization of the phylogenetic diversity of five novel species
RT belonging to the genus Bifidobacterium.";
RL Submitted (SEP-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RSX56534.1}.
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DR EMBL; QXGK01000009; RSX56534.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A430FTZ2; -.
DR Proteomes; UP000287470; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 1.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 2.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000287470};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 286..502
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT DOMAIN 532..862
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
FT REGION 1..28
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 867 AA; 92064 MW; 6540DADC811A5314 CRC64;
MSMTDSFRPS VSSHSARPSQ PARPSHIEVR GARVHNLKDV DIDIPLGELV GVAGVSGSGK
SSLALGVLYA EGSRRYLEAL STYTRRRLTQ ASRAQVDDVR HVPAALALHQ RPAVPGIRST
FGTMSELLNA LRLLFSRVGS HVCPKCGARS EPTLNVAAEL PIRCVGCGEE FYGPGAEDLA
FNSGGACPAC SGTGVVREVD RAALVPDESK SIDDGAVLPW GSLMWDLMKQ VCGAMGVRTN
VPFRELTDEE RQIVFEGPAV KKHILYRPKT GDDFAELDFT YFNAVYTVEN ALAKAKDEKG
LKRVARFLRE GPCHACAGTR LSDRARAPQV AGIDLAQATA MTLDEAVAWV RAVPAGLPEP
MRPMAVNIGE SFLDVARRLL ELGLGYLSLD RAGATLSTGE RQRVQLARAV RNRTTGVLYV
LDEPSIGLHP ANVDGLLGVM RDLVADGNSV VVVDHDVRVL EAADHLVEMG PVAGAGGGRV
LAQGTVAEVA ASADSRIAPF LYRGRRHGGN DGTAASSAVS VSVSVLRVRE QVAVEHMFDY
GAIVLESDAL HTVRPLSVRI PRGRLVAVTG VSGSGKTTMV LETLIPAVRA AAAGEPLPSH
VRSVDAAGIV RANLIDATPI GANVRSTVAT YADVHDDLRR AFARCDEAKA AGWKAGDFSY
NTGRLRCATC DGTGSISLDV QFLPDVDVAC PDCRGSRYAA DASRIRRTGR DGRALTLPQL
MAMSVDEALD ATADLRKVHA RLQTLHDLGL GYLTLGEPTP ALSGGEAQRL KLAGEMGRVQ
SDALFVFDEP TIGLHPSDVR VLLGVFDRLV QAGATVVVIE HDLDVIGEAD WVIDMGPGGG
ESGGRIVAAG TPDDIRRCPE SVTGRYL
//
