ID A0A430KMF1_9GAMM Unreviewed; 393 AA.
AC A0A430KMF1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:RTE64657.1};
GN ORFNames=EH243_16265 {ECO:0000313|EMBL:RTE64657.1};
OS Amphritea opalescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Amphritea.
OX NCBI_TaxID=2490544 {ECO:0000313|EMBL:RTE64657.1, ECO:0000313|Proteomes:UP000283087};
RN [1] {ECO:0000313|EMBL:RTE64657.1, ECO:0000313|Proteomes:UP000283087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANRC-JH13 {ECO:0000313|EMBL:RTE64657.1,
RC ECO:0000313|Proteomes:UP000283087};
RA Fang Z., Zhang Y., Han X.;
RT "The draft genome sequence of Amphritea opalescens ANRC-JH13T.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RTE64657.1}.
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DR EMBL; RQXW01000019; RTE64657.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A430KMF1; -.
DR OrthoDB; 9764638at2; -.
DR Proteomes; UP000283087; Unassembled WGS sequence.
DR GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR CDD; cd00751; thiolase; 1.
DR Gene3D; 3.40.47.10; -; 2.
DR InterPro; IPR002155; Thiolase.
DR InterPro; IPR016039; Thiolase-like.
DR InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR InterPro; IPR020610; Thiolase_AS.
DR InterPro; IPR020617; Thiolase_C.
DR InterPro; IPR020613; Thiolase_CS.
DR InterPro; IPR020616; Thiolase_N.
DR NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR Pfam; PF02803; Thiolase_C; 1.
DR Pfam; PF00108; Thiolase_N; 1.
DR PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR SUPFAM; SSF53901; Thiolase-like; 2.
DR PROSITE; PS00098; THIOLASE_1; 1.
DR PROSITE; PS00737; THIOLASE_2; 1.
DR PROSITE; PS00099; THIOLASE_3; 1.
PE 3: Inferred from homology;
KW Acyltransferase {ECO:0000256|ARBA:ARBA00023315,
KW ECO:0000256|RuleBase:RU003557};
KW Reference proteome {ECO:0000313|Proteomes:UP000283087};
KW Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:RTE64657.1}.
FT DOMAIN 4..262
FT /note="Thiolase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00108"
FT DOMAIN 271..392
FT /note="Thiolase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02803"
FT ACT_SITE 88
FT /note="Acyl-thioester intermediate"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 349
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT ACT_SITE 379
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ SEQUENCE 393 AA; 40842 MW; 6E9595D9B03E344C CRC64;
MRDVVIVAAG RTAVGSFNGS LSSVPASELG TIVIKGLLEK SGIAADQIDE VILGQVLTGG
CGQNPARQAA VNAGLPIEVP AMTINKVCGS GLKSIQLATQ AIRCGDAEMI IAGGQENMSI
SGHILPNSRQ GTRMGDWKMV DTMIKDGLWD AFNDYHMGIT TENIVDKYGF SREEQDVFAA
ASQNKAEAAV TSGKFKDEII PVVMPQRKGD PIVFDTDEQP RFGVTAEALG KLRPAFKKDG
TVTAGNSSTI NDGAAAVILC SAEKAAELGL PVLATIKAYA SAGVDPSIMG TGPICATQKA
LEKAGWTVDD LELIEANEAF AAQALSVNKE LGWDTTLVNV NGGAIALGHP IGASGCRIFV
SLLHEMARRD AKKGLATLCI GGGMGTALAI ERS
//
