ID A0A430KQ08_9GAMM Unreviewed; 988 AA.
AC A0A430KQ08;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 19.
DE RecName: Full=Ion-translocating oxidoreductase complex subunit C {ECO:0000256|HAMAP-Rule:MF_00461};
DE EC=7.-.-.- {ECO:0000256|HAMAP-Rule:MF_00461};
DE AltName: Full=Rnf electron transport complex subunit C {ECO:0000256|HAMAP-Rule:MF_00461};
GN Name=rsxC {ECO:0000313|EMBL:RTE65545.1};
GN Synonyms=rnfC {ECO:0000256|HAMAP-Rule:MF_00461};
GN ORFNames=EH243_11430 {ECO:0000313|EMBL:RTE65545.1};
OS Amphritea opalescens.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Amphritea.
OX NCBI_TaxID=2490544 {ECO:0000313|EMBL:RTE65545.1, ECO:0000313|Proteomes:UP000283087};
RN [1] {ECO:0000313|EMBL:RTE65545.1, ECO:0000313|Proteomes:UP000283087}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ANRC-JH13 {ECO:0000313|EMBL:RTE65545.1,
RC ECO:0000313|Proteomes:UP000283087};
RA Fang Z., Zhang Y., Han X.;
RT "The draft genome sequence of Amphritea opalescens ANRC-JH13T.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Part of a membrane-bound complex that couples electron
CC transfer with translocation of ions across the membrane.
CC {ECO:0000256|HAMAP-Rule:MF_00461}.
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|HAMAP-Rule:MF_00461};
CC Note=Binds 2 [4Fe-4S] clusters per subunit. {ECO:0000256|HAMAP-
CC Rule:MF_00461};
CC -!- SUBUNIT: The complex is composed of six subunits: RnfA, RnfB, RnfC,
CC RnfD, RnfE and RnfG. {ECO:0000256|HAMAP-Rule:MF_00461}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000256|HAMAP-
CC Rule:MF_00461}; Peripheral membrane protein {ECO:0000256|HAMAP-
CC Rule:MF_00461}.
CC -!- SIMILARITY: Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC
CC subfamily. {ECO:0000256|HAMAP-Rule:MF_00461}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RTE65545.1}.
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DR EMBL; RQXW01000009; RTE65545.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A430KQ08; -.
DR OrthoDB; 9767754at2; -.
DR Proteomes; UP000283087; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0009055; F:electron transfer activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR Gene3D; 1.20.58.60; -; 1.
DR Gene3D; 3.30.70.20; -; 1.
DR Gene3D; 3.40.50.11540; NADH-ubiquinone oxidoreductase 51kDa subunit; 1.
DR HAMAP; MF_00461; RsxC_RnfC; 1.
DR InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR InterPro; IPR017900; 4Fe4S_Fe_S_CS.
DR InterPro; IPR010208; Ion_transpt_RnfC/RsxC.
DR InterPro; IPR011538; Nuo51_FMN-bd.
DR InterPro; IPR037225; Nuo51_FMN-bd_sf.
DR InterPro; IPR026902; RnfC_N.
DR NCBIfam; TIGR01945; rnfC; 1.
DR PANTHER; PTHR43034; ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT C; 1.
DR PANTHER; PTHR43034:SF2; ION-TRANSLOCATING OXIDOREDUCTASE COMPLEX SUBUNIT C; 1.
DR Pfam; PF01512; Complex1_51K; 1.
DR Pfam; PF12838; Fer4_7; 1.
DR Pfam; PF13375; RnfC_N; 1.
DR SUPFAM; SSF46548; alpha-helical ferredoxin; 1.
DR SUPFAM; SSF142019; Nqo1 FMN-binding domain-like; 1.
DR PROSITE; PS00198; 4FE4S_FER_1; 1.
DR PROSITE; PS51379; 4FE4S_FER_2; 2.
PE 3: Inferred from homology;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485, ECO:0000256|HAMAP-Rule:MF_00461};
KW Cell inner membrane {ECO:0000256|HAMAP-Rule:MF_00461};
KW Cell membrane {ECO:0000256|HAMAP-Rule:MF_00461};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Electron transport {ECO:0000256|ARBA:ARBA00022982, ECO:0000256|HAMAP-
KW Rule:MF_00461};
KW Iron {ECO:0000256|ARBA:ARBA00023004, ECO:0000256|HAMAP-Rule:MF_00461};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014, ECO:0000256|HAMAP-
KW Rule:MF_00461}; Membrane {ECO:0000256|HAMAP-Rule:MF_00461};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723, ECO:0000256|HAMAP-
KW Rule:MF_00461}; Reference proteome {ECO:0000313|Proteomes:UP000283087};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|HAMAP-Rule:MF_00461};
KW Translocase {ECO:0000256|HAMAP-Rule:MF_00461};
KW Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|HAMAP-Rule:MF_00461}.
FT DOMAIN 365..394
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT DOMAIN 404..433
FT /note="4Fe-4S ferredoxin-type"
FT /evidence="ECO:0000259|PROSITE:PS51379"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 454..489
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 513..711
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 752..779
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 820..982
FT /evidence="ECO:0000256|SAM:Coils"
FT BINDING 374
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 377
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 380
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 384
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 413
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 416
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 419
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="2"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
FT BINDING 423
FT /ligand="[4Fe-4S] cluster"
FT /ligand_id="ChEBI:CHEBI:49883"
FT /ligand_label="1"
FT /evidence="ECO:0000256|HAMAP-Rule:MF_00461"
SQ SEQUENCE 988 AA; 105670 MW; 26E80A655C1A180B CRC64;
MKNTIRVHQF HGGIHPPENK KQSTGAPISL APLPSRIILP LQQHIGLPAD PIVKVGDRVL
KGQRVAEAIG RISANIHASI SGTVVDIGPH PVPHVSGMDA DCLVIESDGQ DEWIEHQGLP
DYTQLAKPEL IEYIRQAGVA GMGGAGFPTD VKLHLGDDHI VNTLIINAAE CEPYITADDM
LMRERADEIL GGIEIIAHLL KPLHIMVGIE DNKPQAIRAL HDALDKSHLN LDIVITPTKY
PSGGEKQLIK LLTGVEVPSG KIPADVGIVC QNVGTTTAVY RAVILGEPLI SRIMTVTGES
ANHKQNYEVR IGTPIADLLN HSGVDRAQMQ RLIIGGPMMG ITVTNEQIPV IKTTNCLIAA
SIHEMPPQPP AQACIRCGMC EQVCPAELLP QQLYWFAKGK EFDKARHHNL FDCIECGACS
YVCPSNIPLV QYYRFAKAEI RKEDDEQRKA DHARLRFEAR LARLERDKIE KEERRKQRAI
EAAAAQAAKK DAAFNKAASP ATNNPTDAGV PDLKQLKSNA AIARTKLRKA EKALANAQDK
GLDGIETLQA TLKQLQLKSE LAEKAYTEAQ QAPAKSAAAP ETDLKQLKSN AAIARTKLKK
AEKQLAAAEA GGEGDIDALK AQVVALQAKS ADAEKAYQAA DSGTVSPVAI DTSALEAEIA
TLQGKVDKAE NAWKAAVESG SPAAEKMAAG VEKLKEKLTG LQAELTQARS AVQPAATVDT
SALDTEIATL QGKVDKAENA WKAAVESGSP AAEKMAAGVE KLKEKLTGLQ AELTQARSAV
QPAATVDTSA LDAEITTLQG KVDKAENAWK AAVESGSPAA DKMAAGVEKL KEKLKGLQAE
LTQAKGHLET NAEGKAEEAP AIDLKALKQQ VSIMRTKLKK AEKQLAELPE GEDNASLMAE
IEALRARHDA AKASFDAAEA DKIAAAASEG IDLKQLKIDA ALARAAVTKA ERALSKAEQE
SKQSLETELL SIRAKADKLN ATLERFSD
//
