ID   A0A431VNV4_9PROT        Unreviewed;       391 AA.
AC   A0A431VNV4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Acetyl-CoA C-acetyltransferase {ECO:0000313|EMBL:RTR24410.1};
GN   ORFNames=EJ903_01180 {ECO:0000313|EMBL:RTR24410.1};
OS   Azospirillum griseum.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Azospirillaceae; Azospirillum.
OX   NCBI_TaxID=2496639 {ECO:0000313|EMBL:RTR24410.1, ECO:0000313|Proteomes:UP000277007};
RN   [1] {ECO:0000313|EMBL:RTR24410.1, ECO:0000313|Proteomes:UP000277007}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=L-25-5w-1 {ECO:0000313|EMBL:RTR24410.1,
RC   ECO:0000313|Proteomes:UP000277007};
RA   Yang Y.;
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the thiolase-like superfamily. Thiolase family.
CC       {ECO:0000256|ARBA:ARBA00010982, ECO:0000256|RuleBase:RU003557}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RTR24410.1}.
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DR   EMBL; RXMA01000001; RTR24410.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A431VNV4; -.
DR   OrthoDB; 9764638at2; -.
DR   Proteomes; UP000277007; Unassembled WGS sequence.
DR   GO; GO:0016747; F:acyltransferase activity, transferring groups other than amino-acyl groups; IEA:InterPro.
DR   CDD; cd00751; thiolase; 1.
DR   Gene3D; 3.40.47.10; -; 2.
DR   InterPro; IPR002155; Thiolase.
DR   InterPro; IPR016039; Thiolase-like.
DR   InterPro; IPR020615; Thiolase_acyl_enz_int_AS.
DR   InterPro; IPR020610; Thiolase_AS.
DR   InterPro; IPR020617; Thiolase_C.
DR   InterPro; IPR020613; Thiolase_CS.
DR   InterPro; IPR020616; Thiolase_N.
DR   NCBIfam; TIGR01930; AcCoA-C-Actrans; 1.
DR   PANTHER; PTHR18919; ACETYL-COA C-ACYLTRANSFERASE; 1.
DR   PANTHER; PTHR18919:SF153; TRIFUNCTIONAL ENZYME SUBUNIT BETA, MITOCHONDRIAL; 1.
DR   Pfam; PF02803; Thiolase_C; 1.
DR   Pfam; PF00108; Thiolase_N; 1.
DR   PIRSF; PIRSF000429; Ac-CoA_Ac_transf; 1.
DR   SUPFAM; SSF53901; Thiolase-like; 2.
DR   PROSITE; PS00098; THIOLASE_1; 1.
DR   PROSITE; PS00737; THIOLASE_2; 1.
DR   PROSITE; PS00099; THIOLASE_3; 1.
PE   3: Inferred from homology;
KW   Acyltransferase {ECO:0000256|RuleBase:RU003557};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277007};
KW   Transferase {ECO:0000256|RuleBase:RU003557, ECO:0000313|EMBL:RTR24410.1}.
FT   DOMAIN          4..260
FT                   /note="Thiolase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00108"
FT   DOMAIN          269..390
FT                   /note="Thiolase C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02803"
FT   ACT_SITE        88
FT                   /note="Acyl-thioester intermediate"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        347
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
FT   ACT_SITE        377
FT                   /note="Proton acceptor"
FT                   /evidence="ECO:0000256|PIRSR:PIRSR000429-1"
SQ   SEQUENCE   391 AA;  40304 MW;  BA7A2B4A107B234F CRC64;
     MTEVVIAAAA RTPIGSFNGA LSSLSAHALG EIAIREALAR AKTDAAEVNE VILGQILTAG
     QGQNPARQAA VNAGIPVEAT AFGINQLCGS GLRAVALGFQ AIKNGDADII VAGGQESMSQ
     AQHTMHLRNG TKMGTASLVD SMLVDGLTDA FKGYHMGTTA ENIATQWQFT REEQDAFAAS
     SQQKAEAAQK AGRFKDEIVP VTIKGRKGDV VVSDDEYPKH GTTAESLAKL RPAFSKDGTV
     TAGNASGIND GAAALVLMSA ENAAKRGVTP LARIVSWATA GVDPSIMGTG PIPASRLALK
     KAGWTIDDLD LIEANEAFAS QAMSVNKDLG WDVSKVNVNG GAIALGHPVG ASGARVLTTL
     LFEMQKRDAK KGLATLCIGG GMGIALCVQR D
//