ID   A0A432VK32_9SPHN        Unreviewed;       359 AA.
AC   A0A432VK32;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Toll/interleukin-1 receptor domain-containing protein {ECO:0000313|EMBL:RUN77143.1};
GN   ORFNames=EJC47_06480 {ECO:0000313|EMBL:RUN77143.1};
OS   Sphingomonas sp. TF3.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC   Sphingomonadaceae; Sphingomonas.
OX   NCBI_TaxID=2495580 {ECO:0000313|EMBL:RUN77143.1, ECO:0000313|Proteomes:UP000275325};
RN   [1] {ECO:0000313|EMBL:RUN77143.1, ECO:0000313|Proteomes:UP000275325}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TF3 {ECO:0000313|EMBL:RUN77143.1,
RC   ECO:0000313|Proteomes:UP000275325};
RA   Afonin A., Vasilieva E., Akhtemova G., Zhukov V.;
RT   "The Draft Genome Sequence of a Sphingomonas sp strain TF3.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUN77143.1}.
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DR   EMBL; RWKS01000006; RUN77143.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A432VK32; -.
DR   Proteomes; UP000275325; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius}; Receptor {ECO:0000313|EMBL:RUN77143.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275325};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        181..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          10..117
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   359 AA;  39264 MW;  D9B0CD11ED2D6802 CRC64;
     MAQSGSYIAF ISYSHSDRYW AEWLHRTLER YRPPRHIGAD LNKPTRLRPI FRDQAELSAG
     PDLGDSIRSA LDRSSHLILL CSPSALASRW VNAELAHFLT THSVDRVLCV LVGDSQPGKS
     LLECLPEGLR EALPVGQEPL AADLRVGGDG RRLARLKLAA GLLGVGLDLL VQRDARRRTR
     LMMAITAAAV SLSVAFGGLA LAAIDARRLA QRQAAESEDL VAFMLGDLRG KLEPVGRLDV
     LDGVGRKVLD HYARIDDDRL DDPALAQQAK ALTLLGSIRV KRADLPGAEQ AFASAAATSA
     RLVARAPHDG TRLFDHAQNV YWLAFVQWKL DHVAAAERGF AEYARLADML VQIDPKRAD
//