ID A0A433HP29_9BACI Unreviewed; 1737 AA.
AC A0A433HP29;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 13-SEP-2023, entry version 16.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=ELQ35_07070 {ECO:0000313|EMBL:RUQ30106.1};
OS Peribacillus cavernae.
OC Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Peribacillus.
OX NCBI_TaxID=1674310 {ECO:0000313|EMBL:RUQ30106.1, ECO:0000313|Proteomes:UP000267430};
RN [1] {ECO:0000313|EMBL:RUQ30106.1, ECO:0000313|Proteomes:UP000267430}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=L5 {ECO:0000313|EMBL:RUQ30106.1,
RC ECO:0000313|Proteomes:UP000267430};
RA Seuylemezian A., Vaishampayan P.;
RT "Bacillus chawlae sp. nov., Bacillus glennii sp. nov., and Bacillus saganii
RT sp. nov. Isolated from the Vehicle Assembly Building at Kennedy Space
RT Center where the Viking Spacecraft were Assembled.";
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUQ30106.1}.
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DR EMBL; RYZZ01000007; RUQ30106.1; -; Genomic_DNA.
DR OrthoDB; 9801841at2; -.
DR Proteomes; UP000267430; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd00075; HATPase; 1.
DR CDD; cd00082; HisKA; 1.
DR CDD; cd14014; STKc_PknB_like; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 3.30.450.40; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR041664; AAA_16.
DR InterPro; IPR003018; GAF.
DR InterPro; IPR029016; GAF-like_dom_sf.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43642; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR PANTHER; PTHR43642:SF1; HYBRID SIGNAL TRANSDUCTION HISTIDINE KINASE G; 1.
DR Pfam; PF13191; AAA_16; 1.
DR Pfam; PF01590; GAF; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00065; GAF; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF55781; GAF domain-like; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50109; HIS_KIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000267430};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT DOMAIN 10..271
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT DOMAIN 1508..1731
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 1467..1508
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1737 AA; 198007 MW; 2BCFCF7D3C9282DD CRC64;
MDDRIFLPGY KLINLETENE TCLFYKAYST VMNKMVLIKV LKTKDLTVHE AASAIHEFHV
GAKLHADSIL QPLTIVKHLN VPYLVFEYFQ CVTLGELLAS YQGNVIDSLT IAANLATALS
LIHQQQVIHK NMNPENILIN PKTFSIKITG FNHATSLKQE NYPAHIGSNS IDGHLAYISP
EQTGRMNRSL DYRTDLYSLG VTLYQLFTGI LPFTSKDPIQ LVHAHLAKTP QNPGDIRKDL
PETVSAIIMK LLSKSPEYRY NSAFGVREDL LNCLNQLQAF GKVEAFLIGL KDKKIVFETA
RKLYGREDEI NKIKSVFNLA AKGELGIVLI PGHSGIGKTA LVNKIHKPLV REKGYFISGK
FDQLQRQVPY APILTAFQSL IRQIMTESPE QIQRWKALLE KELTGNTAVI TSIIPELEWL
LGEHSLDEVT SVDSQKRFLF TFQKFINVFA SKEHPLVLFL DDLQWADVSS LEMIEYLLTQ
ANSRYMMVIG AYRDNEVGVN HPFLKTIQKI REANVPVADI PLQNLQKETI HEWLQDSLLD
NGEKVEQISV FMHRITQGNP FFMKQLLQSY YEDGHIVLHP DKDRWIVELT HITEKPVKEN
IVNFMVERIL MLPEPTQQVL RLASCIGNLF DLKTLSIISE KNYKETAADL WAALEAGLIL
PNDVMYKWIY PDEESRLLEN EPPAYTFLHD RVQQAVYSTM TKEEQELAHL TIGRLLVKFS
DNIDDQLFTI VNHLNASRSH LTQQEILLLT EWNVSAGEKA KASAAFQESL KYFGTAYELA
GANWKDSYHL TFRMMKGLGE CQYLTSRFND AENTFNNILL HSQSVYEKLA IYNLKITLYT
HVHRVKEAVK SGIAGLELFG INLSENPGKA TIIRELALVR IALYGKSKVD LYALPEMTDK
DQKLILQTLI NMNAPTYHVD QNLATLLMLR ALRSTLKYGI TEISALVFNN YSLILSAGFS
DFKGSYEFGN LAIDLSERFG VVSIKGRVQF VYGSFVNHWR NSLSGNLAYL EKSQRYCLDS
GNIHLAGANS SFIVITLFMK GTPIMDTLEG IKNQLQFINQ IQYPISKGFL NELRQWLQFL
SGANTVRTWE FEPVLDDDSA KIIHYTLRLQ MAYLFYKKDY AKELLQSLAP LVNKRLTLVI
APEYYFYHAL WLSRFYDDAV TDREKREIRK RLTQYTKKMK KWAELAPENY LHKYLLLKAE
IARLNKDERS ILPFYDESIH YAEKNGFLQD AAIINECAAR HYAAKGYTKL ANAYMAESYK
TYRTWGANAK AQQLLEEKNS LIETEAVTGL LASQQETDSF FDINAALKAT QSISKEIILE
KLLNKLMHIT MEYGGADRGF LLYTRDNQLV IGEHKSLDET EATVWKHRTI KGTGLISEKI
VDYVETSKEV VVLDDAASIG MFTEDSYVIS KKQRSLLCLP ILHKGSLNGI LYLENNKATH
AFTEGKIKFL TFLSTQAAIS IENAYLYEKL ESKVVKRTAE LKEANHHLEE LNQKMERAEQ
SRRHFLSNIS HDLRAPIASV KGYIEAISDG MINTEAQKDY YLTKSLDRIN DLHLLIHDLF
ELSQLETGQI SFSMDFIPVD RLAGYMYRKY EYDIAKSGLT FKFENQLDPA NGVSPMVEID
LDRMEQVFSN LITNAIKHTK FGEICLTLAG SDNPEQAVIS IRDTGSGIPA EELLLIFDRN
YTKTSKYSTE AGHGLGLSIC KEIITYHKGE IWAESEEGKG TSFYIRLPLI QYAEELV
//
