ID   A0A433RMM8_9BACL        Unreviewed;       298 AA.
AC   A0A433RMM8;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 13.
DE   SubName: Full=MerR family transcriptional regulator {ECO:0000313|EMBL:RUS48929.1};
GN   ORFNames=ELR57_00855 {ECO:0000313|EMBL:RUS48929.1};
OS   Cohnella sp. AR92.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Cohnella.
OX   NCBI_TaxID=648716 {ECO:0000313|EMBL:RUS48929.1, ECO:0000313|Proteomes:UP000267180};
RN   [1] {ECO:0000313|EMBL:RUS48929.1, ECO:0000313|Proteomes:UP000267180}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AR92 {ECO:0000313|EMBL:RUS48929.1,
RC   ECO:0000313|Proteomes:UP000267180};
RX   PubMed=29166641; DOI=10.1159/000480541;
RA   Pisa J.H., Manfredi A.P., Perotti N.I., Romero H.G., Breccia J.D.,
RA   Martinez M.A.;
RT   "Agrowastes as Feedstock for the Production of Endo-?-Xylanase from
RT   Cohnella sp. Strain AR92.";
RL   J. Mol. Microbiol. Biotechnol. 27:277-288(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUS48929.1}.
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DR   EMBL; RZJR01000001; RUS48929.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A433RMM8; -.
DR   Proteomes; UP000267180; Unassembled WGS sequence.
DR   GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR   CDD; cd01104; HTH_MlrA-CarA; 1.
DR   Gene3D; 1.10.1660.10; -; 1.
DR   Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR   Gene3D; 1.10.1240.10; Methionine synthase domain; 1.
DR   InterPro; IPR003759; Cbl-bd_cap.
DR   InterPro; IPR006158; Cobalamin-bd.
DR   InterPro; IPR036724; Cobalamin-bd_sf.
DR   InterPro; IPR009061; DNA-bd_dom_put_sf.
DR   InterPro; IPR000551; MerR-type_HTH_dom.
DR   InterPro; IPR047057; MerR_fam.
DR   InterPro; IPR036594; Meth_synthase_dom.
DR   PANTHER; PTHR30204:SF67; HTH-TYPE TRANSCRIPTIONAL REGULATOR MLRA-RELATED; 1.
DR   PANTHER; PTHR30204; REDOX-CYCLING DRUG-SENSING TRANSCRIPTIONAL ACTIVATOR SOXR; 1.
DR   Pfam; PF02310; B12-binding; 1.
DR   Pfam; PF02607; B12-binding_2; 1.
DR   Pfam; PF13411; MerR_1; 1.
DR   SMART; SM00422; HTH_MERR; 1.
DR   SUPFAM; SSF52242; Cobalamin (vitamin B12)-binding domain; 1.
DR   SUPFAM; SSF46955; Putative DNA-binding domain; 1.
DR   PROSITE; PS51332; B12_BINDING; 1.
DR   PROSITE; PS50937; HTH_MERR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000267180}.
FT   DOMAIN          7..77
FT                   /note="HTH merR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50937"
FT   DOMAIN          181..298
FT                   /note="B12-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51332"
SQ   SEQUENCE   298 AA;  34043 MW;  3A8DBA6EAAADD0FF CRC64;
     MRRERMMYSM KRASELLGIP VVTIRAWENR YGVIAPSRSS GGHRLLSEED LARLRFLKNQ
     IEKHHMKISE AAKLLQQTEP DPPEQAAEQS ATSQKYDGMV DKLYTELIQF DSAQADHTID
     LAFALYDFEE AFRRIIVPVL YRVGEEWEAG NIAVVQEHFA SETIMRRLAA LFRVFPVNAS
     LPVVLAFCPE GEHHHLGLMS FSLFLRKRGA NVIYLGPDTP LKDLDGIIES QNVSLVASSV
     TDSRCVDKLM EWIDAAARKH PRLRFLLGGA AFERAERRPA RAKVRFLSVD QWDDWHKP
//