ID A0A433SU52_ELYCH Unreviewed; 910 AA.
AC A0A433SU52;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=PLAT domain-containing protein {ECO:0000259|PROSITE:PS50095};
DE Flags: Fragment;
GN ORFNames=EGW08_019537 {ECO:0000313|EMBL:RUS72701.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS72701.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS72701.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS72701.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS72701.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the polycystin family.
CC {ECO:0000256|ARBA:ARBA00007200}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00152}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS72701.1}.
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DR EMBL; RQTK01001030; RUS72701.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A433SU52; -.
DR STRING; 188477.A0A433SU52; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR Gene3D; 2.60.60.20; PLAT/LH2 domain; 1.
DR InterPro; IPR013122; PKD1_2_channel.
DR InterPro; IPR003915; PKD_2.
DR InterPro; IPR001024; PLAT/LH2_dom.
DR InterPro; IPR036392; PLAT/LH2_dom_sf.
DR InterPro; IPR046791; Polycystin_dom.
DR PANTHER; PTHR10877:SF183; AT14535P-RELATED; 1.
DR PANTHER; PTHR10877; POLYCYSTIN FAMILY MEMBER; 1.
DR Pfam; PF08016; PKD_channel; 1.
DR Pfam; PF01477; PLAT; 1.
DR Pfam; PF20519; Polycystin_dom; 1.
DR PRINTS; PR01433; POLYCYSTIN2.
DR SMART; SM00308; LH2; 1.
DR SUPFAM; SSF49723; Lipase/lipooxygenase domain (PLAT/LH2 domain); 1.
DR PROSITE; PS50095; PLAT; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 256..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 289..310
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 409..432
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 452..475
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 660..684
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 704..722
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 754..774
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 794..816
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 853..877
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 92..213
FT /note="PLAT"
FT /evidence="ECO:0000259|PROSITE:PS50095"
FT DISULFID 511..524
FT /evidence="ECO:0000256|PIRSR:PIRSR603915-2"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RUS72701.1"
SQ SEQUENCE 910 AA; 104373 MW; 2445488B62BA9438 CRC64;
KVGPLTTKYE TQCFCDHLTS FGSDSSTAPN TIDFNNVWAN FDLSENAAVF STVIVLIGVY
IILLVWLRHM DKKDLKKWGA LPLEDNLPTD SYHYQFTIQT GVKANAGTDS QIRFIVSGEE
GDSGVRRLAV ADGERKHIPR GSILNYVMSV DACLGPLTFL RIWHDNSGKA KNKSWYLDQV
QINDLQTGEK FIFLCDNWLA VEQGDGMVDR ILPVAGIDDL VAFKQLFSSS ARKKLANDHL
WLSVFSRPTR SNFTRVQRLS CCMSLLFLTM ITNAMWFKGE SNNENDRCSL FQFFIGFAST
LIVFPPNFIM MTFFRRCRPK NNAIAQVNQP EIKDKQKFRW KNVNSSSMIW GPKVKKSRLK
KLKESISNIL TLHKKNKYSD DIPAEEISRE DEIELAKPKK KKPWSLPHWC IYIAWVLCFF
SIVASGFFTI LYSMQWGKEK SNEWLTTFLL SFFQSVIIVQ PIKVLLLVAF IACILKKPDL
DEEDLDEDIN KVLAGRAAAG NKDEASLSHT CTIMPELRSI INHCRDEYSW TDDDTKPYLP
HWVTPPGHMV EELEEREDDP FVYQNSFRLK TAPYVGTLAT YKGGGYTILT KRLFCRTDKI
IKRARAQDWL DLNTRAIFLE YTVYNPNINL FASVTAVTEF LTTGSATSRV EVKVFRLMSY
IGGFGLIVLI MEVFFGVTVL YFFYQCVKKV KVHKWKYFND FWSLLEFVLL CFAVACIVLY
AFKHILTEVA MRALHNRKSD GFVNFNSIAL YDELYGWIMA VVVFMATIQF LKLLQFNKKM
GMLGSTIKLA SKDLKVFSIT FFLYFFAFTG TAFLLFGHVL MSYQSIVTAA ESMFAFALGS
FDYEAMTRAQ PFWGPLFFFS YIGVVYIGLM SIFLTIIGDS FTTVKENVAL QSNDYEIVDF
MWKKLKGLFN
//
