ID A0A433SXU4_ELYCH Unreviewed; 534 AA.
AC A0A433SXU4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=3'-5' exonuclease domain-containing protein {ECO:0008006|Google:ProtNLM};
DE Flags: Fragment;
GN ORFNames=EGW08_018118 {ECO:0000313|EMBL:RUS74111.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS74111.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS74111.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS74111.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS74111.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS74111.1}.
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DR EMBL; RQTK01000864; RUS74111.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A433SXU4; -.
DR STRING; 188477.A0A433SXU4; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0008408; F:3'-5' exonuclease activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0006139; P:nucleobase-containing compound metabolic process; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR002562; 3'-5'_exonuclease_dom.
DR InterPro; IPR002782; Mut7-C_RNAse_dom.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR47765; 3'-5' EXONUCLEASE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR47765:SF2; EXONUCLEASE MUT-7 HOMOLOG; 1.
DR Pfam; PF01612; DNA_pol_A_exo1; 1.
DR Pfam; PF01927; Mut7-C; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974}.
FT DOMAIN 28..84
FT /note="3'-5' exonuclease"
FT /evidence="ECO:0000259|Pfam:PF01612"
FT DOMAIN 156..266
FT /note="Mut7-C RNAse"
FT /evidence="ECO:0000259|Pfam:PF01927"
FT DOMAIN 325..362
FT /note="Mut7-C RNAse"
FT /evidence="ECO:0000259|Pfam:PF01927"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 101..146
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 379..465
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..16
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 101..117
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..135
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..428
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RUS74111.1"
SQ SEQUENCE 534 AA; 59119 MW; 1271FF9DE1156E42 CRC64;
VRLDPDSQEE KQSRKCDQGF GSGQFQKSEE KGLSLLVRKT LGKPLSKDEQ MSNWEKRPLR
PTQIAYAASD AYVLLDVYQA LRSRGEAMGL SRSDLEPLTS FKLKTRMDKK KERVSGTKQS
SSKQQKSTQS PVVEPKPSVS GPEPQGGAMI HPYELRVVCN NMLQGLGSQL RACGVDTVIL
GPNLKHTEAI KISNCENRIV LSSGKVFEQI RAAVGGGMCL RVPHTIPCLE QCVFVLKHFR
VNVQREDIFS RCAMCNGTEF VDIPSKDLET LSVFALQQQS MAGQYAGVRH DGSACDVDPD
TQAKFRQYGI DPVSISFLHN RVRIQVETVP SRKMFQSIVY FFVCWSCGKV YWEGSHYENI
STQFADILHL NGGVVSGTAS GSGKDGNAGN KIVKPVDERP SSSRPKVKQN QGNVGRDNDS
NSVASPQAGG SARGGKAKTK TGKKQKFDGH QRNQDNRLAG LGRGYSSRDP FDDALGLRED
YLQPSGLDTI NDLHYGFDEW EADPYCDSTD FRDVLVDDPL MYTYGEDAGY DYMF
//
