ID A0A433TC35_ELYCH Unreviewed; 1360 AA.
AC A0A433TC35;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=EGF-like domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=EGW08_013175 {ECO:0000313|EMBL:RUS79070.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS79070.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS79070.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS79070.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS79070.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00076}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS79070.1}.
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DR EMBL; RQTK01000473; RUS79070.1; -; Genomic_DNA.
DR STRING; 188477.A0A433TC35; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00054; EGF_CA; 2.
DR CDD; cd00110; LamG; 5.
DR Gene3D; 2.60.120.200; -; 6.
DR Gene3D; 2.10.25.10; Laminin; 2.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR000742; EGF-like_dom.
DR InterPro; IPR001791; Laminin_G.
DR PANTHER; PTHR15036:SF89; NEUREXIN 1, ISOFORM F; 1.
DR PANTHER; PTHR15036; PIKACHURIN-LIKE PROTEIN; 1.
DR Pfam; PF02210; Laminin_G_2; 6.
DR SMART; SM00181; EGF; 2.
DR SMART; SM00282; LamG; 5.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 6.
DR PROSITE; PS50026; EGF_3; 2.
DR PROSITE; PS50025; LAM_G_DOMAIN; 5.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW EGF-like domain {ECO:0000256|PROSITE-ProRule:PRU00076};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 1285..1307
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 1..189
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 185..223
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 228..417
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 424..606
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 744..922
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT DOMAIN 925..962
FT /note="EGF-like"
FT /evidence="ECO:0000259|PROSITE:PS50026"
FT DOMAIN 966..1153
FT /note="Laminin G"
FT /evidence="ECO:0000259|PROSITE:PS50025"
FT REGION 95..118
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1181..1279
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1329..1360
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1210..1230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1346..1360
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1360 AA; 149423 MW; 0317ADEA6393C8F6 CRC64;
MTCLNGSFSL EFKTYDKNGL LFYIQKGSNL FLELKLSGEH LKLRADFGTG DVEMTSALVP
LALVDGNWQS VEVIRKSDVV ELKVNNAALA TTSISKSSLS SPPSSPNSLS SSSLDQQSPA
ENESFAFIGG FPREYDSKKS GTLAVPLVEF EPRFRGSVRN LFYRNCSGVT LRPEMLSSSG
ILTHDVDRCL NDNPCLNGGR CLTTDDGRIC ECKNTEYEGD RCEIQKNPSD ATFLGAQYIS
YDLTNKGGVM VSNDDNINLD FRTKQSNAFL LYIGNFKDYI IVVLKDGVIT VQINLGSGIL
KKVINPKNVR FDDNNWHQLH IRREAQYLNI EVDGMYMASG STTGAFAHLS SSVFYLAGHP
KNSQRLATGD YDDIPNFKGC MRKVVYKANN IRIDLTTLAR EGHSLLKIVG DVHFDKCQEL
ADSRPVTFAT PDAYITVATW DKSRSKGSIA FQFRTVEQNG LLMYSNGNRD SKDFFALEFM
DGNLYLVFNM GSGIHKKKAT EVSLSDGYPH DVFFEFHNYA GSISVDGRKT SFETHVVSDR
FDLHGELYVG GIGPAVNVSA LPREIWSALG GFFYVGCLQD LVVNGNMVDI AGNARQQNRT
DVVGYCQKIL SAGHTLGDDR WHTVFIRRRL GVVEVSIDGD RPVRDVIPSH TFTMKTSEIF
VGRTASPQRD GTELFHMPHR KRSVQPSSLM LRDHSAWPAS YSGFIGSMQS FLFNGKDIFQ
MASLGHANIE KTAQVDPDEH VVREPITFKS VDAYAALNGL VLQTEYHISM QFKTTEKNGL
ILYNGGSGND FLALELSNGF LYYVYNMGEG EQRVRANVIQ HLSDNKWHEL RVYRTEISQQ
MIRVDDRTPT IDDLSGAKNR KFDLDGKLYL GGVEKTMYPS LPKMITSRHG FVGCLGSIDL
NRYHPNVMRE AKPITESVGD GCRGPITKCV NDSCANFGRC VQQWNTYSCD CDMTSYTGPM
CTDESVSYSF GPRPGLITFT YPSEQAPSTQ SDSLAFGFQT HMENAVLLRI DSIDSGDFIQ
IELLKGNVYV VYNMGTLDHP IGSFSRKTND GNYHVVRFTR AEANATLQVD SEIPLRKIPT
GKQSHIFNNQ AYIKIGGDRA INQSIVKHFE GTISGKPDLF TDDEDLGEMQ STQPHTTSKE
GVTEDIIYAG SGCHYDSAED CSVIGSGTGD EIITGVVVVS STTTTPRPDP TDKPIPPCKG
HDCESSSRLR LTPGPGNTLS PIGGQGSGSD TRSRSEKDGN SYEVNGQIGI GNGGFGGQQG
IGDYDEDSTA PSDKSSGKGG SSINLGLILG VLGSVLLAVI VLAIAFCKLR SRDEGTYKVD
ETQNFSALQS KKTQGNGAMA SGGEASGKRG KKKDVKEWYV
//
