ID A0A433TGM2_ELYCH Unreviewed; 1683 AA.
AC A0A433TGM2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=PDZ domain-containing protein {ECO:0000259|PROSITE:PS50106};
DE Flags: Fragment;
GN ORFNames=EGW08_011580 {ECO:0000313|EMBL:RUS80676.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS80676.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS80676.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS80676.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS80676.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC Membrane {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS80676.1}.
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DR EMBL; RQTK01000379; RUS80676.1; -; Genomic_DNA.
DR STRING; 188477.A0A433TGM2; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR CDD; cd00992; PDZ_signaling; 3.
DR Gene3D; 2.30.42.10; -; 4.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 3.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR23119; DISCS LARGE; 1.
DR PANTHER; PTHR23119:SF44; PROTEIN SCRIBBLE HOMOLOG; 1.
DR Pfam; PF00560; LRR_1; 3.
DR Pfam; PF13855; LRR_8; 1.
DR Pfam; PF00595; PDZ; 3.
DR SMART; SM00364; LRR_BAC; 9.
DR SMART; SM00365; LRR_SD22; 7.
DR SMART; SM00369; LRR_TYP; 10.
DR SMART; SM00228; PDZ; 3.
DR SUPFAM; SSF52058; L domain-like; 2.
DR SUPFAM; SSF50156; PDZ domain-like; 4.
DR PROSITE; PS51450; LRR; 4.
DR PROSITE; PS50106; PDZ; 3.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 811..899
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 938..1026
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT DOMAIN 1340..1430
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 508..745
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1058..1100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1129..1238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1257..1298
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1433..1683
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 508..591
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 659..677
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 692..745
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1129..1159
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1182..1238
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1275..1298
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1443..1475
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1476..1509
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1538..1587
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1636..1683
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:RUS80676.1"
FT NON_TER 1683
FT /evidence="ECO:0000313|EMBL:RUS80676.1"
SQ SEQUENCE 1683 AA; 181267 MW; 5D8BA85925990C00 CRC64;
SLARKTRYEV FTHSLSDHHV NVLQLSLLLD LLGSIHASTE DKRFNCFVML KCIPLFRACN
RQVESVDRRH WGLTNVPDDV MRYARSLEEL LLDANQIKEL PRAFFRLIQL RKLSLSDNEI
GRLPDEICNF VNLMELDISK NEIFEIPDKI KLCKNLQVLD FSSNPLAKGL PDGLLHLRNL
TQLGLNDVAL QRLPNDISNL TSLGSLELRD NMLKILPDSI SFLIKLKILD LGSNDLETLP
PSIGSLPALE ELWLDCNYLT DLPPEIGNLR KLSILDLSEN QLDYLPDEID GLQSLTDLCL
SQNGLEYLPD GIGNLKKLSI LKADMNRLLA LTPYIGSCEN MQELILTENL LSDLPNSIGK
LKNLHNLNVD RNRLTEIPVE IGICKCLGVL SMRDNKLLRL PQELGNLSKL QVLDVSGNRL
EYLPMTIANL NLKALWLSEN QAQPMLKFQT DFDERTGQRV LTCFLLPQQG FHTESMENLL
KGSIATEGSF TEKDRPRDSV IRFVEDHEKV DDGADSDDST HFVRHDTPHP RELKARHQKF
IKDRNIDGHV IPHMDNKDGS AFVPSRDQDH YYEDDDEAPG PYYKEYDREP SPATHQMLNS
TYTKSPLHDG RGEDTQAPPS PRPVAPDVIK APELTGTPSS TTQPDSSSSE DEDFRQESQP
MLTGRSVTLS TTPTVRIAAN DVEEIDDSRD VEADRDDSST SERVQKSSDE ESDDDNLQRD
RKVGFAPEVD EESSKDHRLR RRDTPHYLKN KRVHKEEDAE QKVLEILAQA AKQRDGAALS
PVVKPPELET MAAPTPATQQ LPVEVQEEEI TIHILREPRQ GLGISIAGGQ GSTPVKGDDE
SIFISRVTED GPAGKAGIMR GDKLLKVNNS SLVGADHYEA VNVLKNSGND ITMVVAREKL
VANAHAEASE LVDSTHESVT TVSFSAEPET EVYGETVTVN LLRDDTGLGF SIAGGRGSVP
YKGNDRAIYI SKITAGGTAD KSGKLQIGDR IVSINDVDLA DARHDQAVNL LTGLDRSIKL
VVYREKVVPK GEGAALAPPG SQRIPSITQP VINWQASNSA APAPARTPSP AGAQQQHLVQ
TSSLASGPAQ PSATPGLTTV VPASVPNSPF SSAVPTSYSY LSQPAASTLT LPDTPASQRA
TSSPSSPRTL SSDWTAPATT IQPPKFVYPG MNRPPSSTPS APAPSHSVAI GSSLSSSPSS
SVVTAPSSAA AASSSPSPSS YSSSPSQRTS TTLLPSQTLN LSPVTLQVSR TPAATLSAKL
AGDHSAPARD ELAKVSNQSP DSNHVDSGTG SISPQPYPIE VNNKDLRNAS HQEAVMALIA
PTYEIHLTVR HDPPPPGLQE LTIDKDPGEK LGLSIKGGAK HLATPDRSDE GIFISRINED
GAAARDGRLK PGQRILEVNG QSLLGSSHQE AVRALRSIGD KLTILVCDQP VAAPPSPSPA
AGATDKGSET NSPAELSSPS SQGGFLASSL AGSSSSIDRE DEDTRILQQE QEMLKEAEQW
ERDQQVLKQQ KRQSVEGPSV ADHLQSLSVA APSWAAPPSA GPLSPPLPSP PPPALPATLP
PDLASTPPPS PLEPSALPPP PPTPTLAEDE DLSPSILPSQ PPDVVADLPP PPISTTRAGG
SNPPSRIPVG RPGTDSHGPT SPSSGIPVAV NSSDQFTTPG SSSPISSPAS KIPVLASSIS
LSP
//
