ID A0A433TTX8_ELYCH Unreviewed; 1143 AA.
AC A0A433TTX8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE RecName: Full=Cadherin domain-containing protein {ECO:0000259|PROSITE:PS50268};
GN ORFNames=EGW08_007209 {ECO:0000313|EMBL:RUS85025.1};
OS Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC Plakobranchidae; Elysia.
OX NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS85025.1, ECO:0000313|Proteomes:UP000271974};
RN [1] {ECO:0000313|EMBL:RUS85025.1, ECO:0000313|Proteomes:UP000271974}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=EC2010 {ECO:0000313|EMBL:RUS85025.1};
RC TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS85025.1};
RA Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RUS85025.1}.
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DR EMBL; RQTK01000185; RUS85025.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A433TTX8; -.
DR STRING; 188477.A0A433TTX8; -.
DR Proteomes; UP000271974; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0005509; F:calcium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0007156; P:homophilic cell adhesion via plasma membrane adhesion molecules; IEA:InterPro.
DR CDD; cd11304; Cadherin_repeat; 7.
DR Gene3D; 2.60.40.60; Cadherins; 7.
DR InterPro; IPR002126; Cadherin-like_dom.
DR InterPro; IPR015919; Cadherin-like_sf.
DR InterPro; IPR020894; Cadherin_CS.
DR InterPro; IPR013164; Cadherin_N.
DR PANTHER; PTHR24028:SF340; CADHERIN 96CB, ISOFORM D-RELATED; 1.
DR PANTHER; PTHR24028; CADHERIN-87A; 1.
DR Pfam; PF00028; Cadherin; 6.
DR Pfam; PF08266; Cadherin_2; 1.
DR PRINTS; PR00205; CADHERIN.
DR SMART; SM00112; CA; 7.
DR SUPFAM; SSF49313; Cadherin-like; 7.
DR PROSITE; PS00232; CADHERIN_1; 2.
DR PROSITE; PS50268; CADHERIN_2; 7.
PE 4: Predicted;
KW Calcium {ECO:0000256|ARBA:ARBA00022837, ECO:0000256|PROSITE-
KW ProRule:PRU00043}; Cell adhesion {ECO:0000256|ARBA:ARBA00022889};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..25
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 26..1143
FT /note="Cadherin domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5019194269"
FT TRANSMEM 806..828
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 62..140
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 141..256
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 257..362
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 376..472
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 473..575
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 576..682
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT DOMAIN 686..803
FT /note="Cadherin"
FT /evidence="ECO:0000259|PROSITE:PS50268"
FT REGION 840..862
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 876..1078
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1097..1143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 907..955
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 973..993
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1000..1041
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1131
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1143 AA; 124612 MW; 343EBFEFD0E1FDA3 CRC64;
MVCFHFPRMT TLLTLVLLLV SVAEAQSAGQ PTVAFEIQEE MLPPVLMGNI GASANISSVP
DLAYSLLQQG GSFENLFEVD ESSGDIRTRT ALDREELCGS LAHCVLRGSV LVSSTSESNF
IRRFQVNITV VDANDQRPMW ASSPYSIEIS ERAAVNSTFQ LPVAEDKDYE PLFRVQSYAL
QSASSSAFEL DVRQTTNSDG YIIFEVYLRL ARKLDRERKE RYTMTLVAYD GHGPTNNGML
PLVVKVGDEN DNAPKFSVTR YVRSVQDVTP PGTTVLKVTA VDADAGENAR VGYMFPNEVD
KRIQELFRLD PVTGDLKLNQ SLGKETSLTF KVRAFDHGKT AMSSDAEVVI NIEDTLNDPP
RMKMSHVDFN GTVDFVKENA ALKKIVAFVE AIDNDGGDNG RVNCSVTDEY FELNTFSPDN
NYVLVVAKEL DRETQDIHKL VINCVDHGSP ALTSSVDMTI VVTDVNDFSP EFSKQVYRMS
VRENQQKNAV VGPVHAEDGD EGANGDVRYS LPANVVKFAI DADGLITTAV RDLDRELQDI
YRFEVYAFDM AVPPRTATAS VVVVVEDLND EWPTFDLSSY HFQISEKAPV GVEIGKLHAN
DKDLGKGGVV EYLLVHAPLH PNPPFSLSQV NGSMTLNREL DFEVEAQYKF VVTAIDLGDP
PRSSTVEVVI DLIDENDNSP IITFPSSDNL SVTLNLNVIP GHEVIQVIAH DADSGDNGRL
SYTMTAAPNT SLDDAVSRLF WMNEDTGLVT LVAPLTPADA HRYDIVVNVQ DHGSSPQRAT
QAMLLVQVVH TLDQASSSRR ESYTTIVIAM VCVTLLVAVV VLLILCYIKY SDRRKYLKSK
NSDGHHHLHK HSHADHQLSD KPVVFDPASG KYDLFTLENN GSIDGHDGSG DRSVDPFDPS
MSPSLQKEPM MGHQNHTRVG STSRGGKKSV TFNSEVRSSD NSLPHSGSTS TVLQDPAPLG
REDRYGVSPV PSQYLPNGRN FSSSQSHSIT FHPNIPVPHN ELVSQRTHSL SPSPLSLQQD
SQNKHAGWTG GSTSSFRSGA AASPSPYPLV SSGAAVYPCD TPRAGPGPQA GSSGQSSDDV
VGVALQKHNA LVRSMRANGR RPHYGQARRT SGEADICSSS SVETNDSGHG GSELDVSVLK
ANV
//
