ID   A0A433U6I0_ELYCH        Unreviewed;       501 AA.
AC   A0A433U6I0;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:RUS89427.1};
DE   Flags: Fragment;
GN   ORFNames=EGW08_002800 {ECO:0000313|EMBL:RUS89427.1};
OS   Elysia chlorotica (Eastern emerald elysia) (Sea slug).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Mollusca; Gastropoda;
OC   Heterobranchia; Euthyneura; Panpulmonata; Sacoglossa; Placobranchoidea;
OC   Plakobranchidae; Elysia.
OX   NCBI_TaxID=188477 {ECO:0000313|EMBL:RUS89427.1, ECO:0000313|Proteomes:UP000271974};
RN   [1] {ECO:0000313|EMBL:RUS89427.1, ECO:0000313|Proteomes:UP000271974}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=EC2010 {ECO:0000313|EMBL:RUS89427.1};
RC   TISSUE=Whole organism of an adult {ECO:0000313|EMBL:RUS89427.1};
RA   Cai H., Li Q., Fang X., Li J., Curtis N.E., Altenburger A., Shibata T.,
RA   Feng M., Maeda T., Schwartz J.A., Shigenobu S., Lundholm N., Nishiyama T.,
RA   Yang H., Hasebe M., Li S., Pierce S.K., Wang J.;
RT   "A draft genome assembly of the solar-powered sea slug Elysia chlorotica.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the amiloride-sensitive sodium channel (TC
CC       1.A.6) family. {ECO:0000256|RuleBase:RU000679}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUS89427.1}.
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DR   EMBL; RQTK01000056; RUS89427.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A433U6I0; -.
DR   STRING; 188477.A0A433U6I0; -.
DR   Proteomes; UP000271974; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005272; F:sodium channel activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.470.10; Acid-sensing ion channels like domains; 1.
DR   InterPro; IPR001873; ENaC.
DR   PANTHER; PTHR11690:SF297; -; 1.
DR   PANTHER; PTHR11690; AMILORIDE-SENSITIVE SODIUM CHANNEL-RELATED; 1.
DR   Pfam; PF00858; ASC; 1.
DR   PRINTS; PR01078; AMINACHANNEL.
PE   3: Inferred from homology;
KW   Ion channel {ECO:0000256|RuleBase:RU000679};
KW   Ion transport {ECO:0000256|RuleBase:RU000679};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000271974};
KW   Sodium {ECO:0000256|ARBA:ARBA00023053};
KW   Sodium channel {ECO:0000256|ARBA:ARBA00022461,
KW   ECO:0000256|RuleBase:RU000679};
KW   Sodium transport {ECO:0000256|ARBA:ARBA00023201,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU000679};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|RuleBase:RU000679}.
FT   TRANSMEM        127..148
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        160..177
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          205..250
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        206..242
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         501
FT                   /evidence="ECO:0000313|EMBL:RUS89427.1"
SQ   SEQUENCE   501 AA;  56687 MW;  9A499C942B70258B CRC64;
     MPRPWEYNPY DTGSVWEPDA DYEDIEKDTT MDSKIKRSEP LQTIGDIFFQ GGDLNHRSYA
     DYTQDVTPGG RGSDYVPGQL HADGAHHDED AEGNPKTFKR VLVRFAERTS MQGVPYIYVS
     SVWYAKLGWS LLFLVGFGLM VGHLYLLIDE FYQYDTHSTV GLGFSTLTFP AVTICNVNPI
     RRSQLYLATP ELRALVDAVQ PSNIAGSMEE ERNKNQPSDN GGQAGSQTPD NSQTPQTGPT
     RRRRSLNEIH EEQIKRRYKR FIEGFSIEES NNRKVDDEDI GGLSGNKSTI RAIEDEFRFL
     YSIMGRNERN EMGHDIDNML MECTFRGITC TADQFRLLQT AQYGNCYTIE NKKYISTVGG
     PDDGLTMYLF SEDEEYLHGI TNSMGFQIHI HNLGELPNPY SEGLSVSAGM ETFIGLKKVN
     IERLQQPYGE CVENEDFQSL YNITYTQRTC QAFCLQKKIV EKCGCFDAEN DSIFKTLADA
     RMVPPPQGNG SQGYSPCRTE S
//