ID   A0A433WII5_9BACT        Unreviewed;       309 AA.
AC   A0A433WII5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 12.
DE   SubName: Full=Hydroxyacid dehydrogenase {ECO:0000313|EMBL:NSL89944.1};
GN   ORFNames=ECE50_024095 {ECO:0000313|EMBL:NSL89944.1};
OS   Chitinophaga solisilvae.
OC   Bacteria; Bacteroidota; Chitinophagia; Chitinophagales; Chitinophagaceae;
OC   Chitinophaga.
OX   NCBI_TaxID=1233460 {ECO:0000313|EMBL:NSL89944.1, ECO:0000313|Proteomes:UP000281028};
RN   [1] {ECO:0000313|EMBL:NSL89944.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Mgbs1 {ECO:0000313|EMBL:NSL89944.1};
RA   Goh C.B.S., Lee M.S., Parimannan S., Pasbakhsh P., Yule C.M., Rajandas H.,
RA   Loke S., Croft L., Tan J.B.L.;
RT   "Chitinophaga laudate sp. nov., isolated from a tropical peat swamp.";
RL   Submitted (MAY-2020) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the D-isomer specific 2-hydroxyacid
CC       dehydrogenase family. {ECO:0000256|ARBA:ARBA00005854,
CC       ECO:0000256|RuleBase:RU003719}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:NSL89944.1}.
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DR   EMBL; RIAR02000001; NSL89944.1; -; Genomic_DNA.
DR   Proteomes; UP000281028; Unassembled WGS sequence.
DR   GO; GO:0051287; F:NAD binding; IEA:InterPro.
DR   GO; GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.
DR   GO; GO:0006807; P:nitrogen compound metabolic process; IEA:UniProt.
DR   GO; GO:0071704; P:organic substance metabolic process; IEA:UniProt.
DR   GO; GO:0044281; P:small molecule metabolic process; IEA:UniProt.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 2.
DR   InterPro; IPR006139; D-isomer_2_OHA_DH_cat_dom.
DR   InterPro; IPR006140; D-isomer_DH_NAD-bd.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   PANTHER; PTHR42789; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR   PANTHER; PTHR42789:SF1; D-ISOMER SPECIFIC 2-HYDROXYACID DEHYDROGENASE FAMILY PROTEIN (AFU_ORTHOLOGUE AFUA_6G10090); 1.
DR   Pfam; PF00389; 2-Hacid_dh; 1.
DR   Pfam; PF02826; 2-Hacid_dh_C; 1.
DR   SUPFAM; SSF52283; Formate/glycerate dehydrogenase catalytic domain-like; 1.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   3: Inferred from homology;
KW   NAD {ECO:0000256|ARBA:ARBA00023027};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000256|RuleBase:RU003719};
KW   Reference proteome {ECO:0000313|Proteomes:UP000281028}.
SQ   SEQUENCE   309 AA;  34122 MW;  75EF1A386CAC867D CRC64;
     MSRKVLITAK THPYLTDQLQ NKGFEVIYAP AITYDEVYST IADCVGLIVT TRVRVDKHII
     DHARELQWIG RLGSGMELID VPYAESKGIH CVSSPEGNRD AVGEQAVGML LCLMNNVLKS
     NLELRQGLWE RDLNRGFELN GRTVGIIGYG NTGSTLARKL SGFDVNILAY DKYLKGFSTA
     GVQEASLERI FAEAEIVSLH LPLTPETHHI GNHDFFASFA RPIWFMNTAR GKLVNNGDLI
     KALQEGKVAG ACLDVIENEK LPTYTAAEKE QLAFFLAAPN VVLTPHIAGY SHEASVKMAR
     IVLEKLNII
//