ID   A0A434AY02_9BACT        Unreviewed;       866 AA.
AC   A0A434AY02;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=DNA gyrase/topoisomerase IV subunit A {ECO:0000313|EMBL:RUT79338.1};
GN   ORFNames=DLK05_03705 {ECO:0000313|EMBL:RUT79338.1};
OS   Ancylomarina longa.
OC   Bacteria; Bacteroidota; Bacteroidia; Marinilabiliales; Marinifilaceae;
OC   Ancylomarina.
OX   NCBI_TaxID=2487017 {ECO:0000313|EMBL:RUT79338.1, ECO:0000313|Proteomes:UP000282985};
RN   [1] {ECO:0000313|EMBL:RUT79338.1, ECO:0000313|Proteomes:UP000282985}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=T3-2 S1-C {ECO:0000313|EMBL:RUT79338.1,
RC   ECO:0000313|Proteomes:UP000282985};
RA   Fu T.;
RT   "Parancylomarina longa gen. nov., sp. nov., isolated from sediments of
RT   southern Okinawa.";
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP-dependent breakage, passage and rejoining of double-
CC         stranded DNA.; EC=5.6.2.2; Evidence={ECO:0000256|ARBA:ARBA00000185};
CC   -!- SIMILARITY: Belongs to the type II topoisomerase GyrA/ParC subunit
CC       family. {ECO:0000256|ARBA:ARBA00008263}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RUT79338.1}.
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DR   EMBL; RJJX01000003; RUT79338.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A434AY02; -.
DR   OrthoDB; 9806486at2; -.
DR   Proteomes; UP000282985; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003918; F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity; IEA:UniProtKB-EC.
DR   GO; GO:0006265; P:DNA topological change; IEA:InterPro.
DR   Gene3D; 3.30.1360.40; -; 1.
DR   Gene3D; 3.90.199.10; Topoisomerase II, domain 5; 1.
DR   Gene3D; 1.10.268.10; Topoisomerase, domain 3; 1.
DR   InterPro; IPR013760; Topo_IIA-like_dom_sf.
DR   InterPro; IPR013758; Topo_IIA_A/C_ab.
DR   InterPro; IPR013757; Topo_IIA_A_a_sf.
DR   InterPro; IPR002205; Topo_IIA_dom_A.
DR   PANTHER; PTHR43493:SF5; DNA GYRASE SUBUNIT A, CHLOROPLASTIC_MITOCHONDRIAL; 1.
DR   PANTHER; PTHR43493; DNA GYRASE/TOPOISOMERASE SUBUNIT A; 1.
DR   Pfam; PF00521; DNA_topoisoIV; 1.
DR   SMART; SM00434; TOP4c; 1.
DR   SUPFAM; SSF56719; Type II DNA topoisomerase; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000313|EMBL:RUT79338.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000282985};
KW   Topoisomerase {ECO:0000256|ARBA:ARBA00023029}.
FT   DOMAIN          30..465
FT                   /note="DNA topoisomerase type IIA"
FT                   /evidence="ECO:0000259|SMART:SM00434"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          844..866
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..15
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   866 AA;  98860 MW;  75E8F729840AD1ED CRC64;
     MSSEETNDME NPEEEEKELN GAQPEAMRNV TYLSGMYQNW FLDYASYVIL ERAVPYVNDG
     LKPVQRRILH AMKRLDDGRY NKVANIIGNT MQYHPHGDAS IGDALVQLGQ KDLLIDMQGN
     WGNILTGDSA AAPRYIEARL SKFALEVVFN AKTTNWKLSY DGRNKEPITL PVKFPLLLAQ
     GVEGIAVGLA SKILPHNFNE LIKACIAYLR EEEFVLYPDF PTAGMIEVSR YNDGLRGGAV
     KVRAKIEKED NKTLKITQIP YGRNTTSLID SIIKANDKGK IKIKKIDDNT AADVEIMIHL
     ASGISSDKTI DALYAFTDCE ISISPNACII ENDKPKFIGV SEILKRSADN TVALLKLELE
     IRKKELEEAW HYASLERIFI ENKIYRDIEE CETWESVLET IDKGLKPFTQ NLMRAVTPDD
     IVRLTEIKIK RISKFDMDKA MDLIKAIESE IEEINVHIAN IIPYTIRYFQ AIKKKFGKGR
     ERKTEIRSFE NIVATKVVVA NQKLYVNYEE GFLGTALKKD KYVCDCSDID DVIIFRKDGT
     YFVTKVADKL FIGKNILHIA IFRKNDKRTI FNVAYRDGRG GNSYVKRFPV TSITRDKEYN
     LTKETTGSRV IYFSANPNGE AEVIRIVLKP KPRLKKLNFE FDFAELAVKG RASMGNILTR
     NDVHKITLKH EGVSTLGGRK IWFDPDVLRL NTDHRGDFIG EFSGEDKILI ISKPASFHFT
     SFDLSNHYAD NISIIEKYDP EKIWSAVFYD ADQEYYYLKR FTMEGNGKTV DFIGENPNNK
     LICLTDESYP RFEITYGGKN EDRPKDIVEG IDFIGVKSHK ARGKRLSIYE IKKIVELDPL
     PREENSEELV LEKPDVDKQN DINSEK
//