ID A0A436ZPI5_9PEZI Unreviewed; 482 AA.
AC A0A436ZPI5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=3-hydroxyisobutyryl-CoA hydrolase {ECO:0000256|ARBA:ARBA00011915};
DE EC=3.1.2.4 {ECO:0000256|ARBA:ARBA00011915};
GN ORFNames=DFL_008606 {ECO:0000313|EMBL:RVD80712.1};
OS Arthrobotrys flagrans.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Arthrobotrys.
OX NCBI_TaxID=97331 {ECO:0000313|EMBL:RVD80712.1, ECO:0000313|Proteomes:UP000283090};
RN [1] {ECO:0000313|EMBL:RVD80712.1, ECO:0000313|Proteomes:UP000283090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS H-5679 {ECO:0000313|EMBL:RVD80712.1,
RC ECO:0000313|Proteomes:UP000283090};
RA Youssar L., Wernet V., Hensel N., Hildebrandt H.-G., Fischer R.;
RT "Intercellular communication is required for trap formation in the
RT nematode-trapping fungus Duddingtonia flagrans.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=3-hydroxy-2-methylpropanoyl-CoA + H2O = 3-hydroxy-2-
CC methylpropanoate + CoA + H(+); Xref=Rhea:RHEA:20888,
CC ChEBI:CHEBI:11805, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC ChEBI:CHEBI:57287, ChEBI:CHEBI:57340; EC=3.1.2.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001709};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVD80712.1}.
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DR EMBL; SAEB01000012; RVD80712.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A436ZPI5; -.
DR STRING; 97331.A0A436ZPI5; -.
DR VEuPathDB; FungiDB:DFL_008606; -.
DR Proteomes; UP000283090; Unassembled WGS sequence.
DR GO; GO:0003860; F:3-hydroxyisobutyryl-CoA hydrolase activity; IEA:UniProtKB-EC.
DR CDD; cd06558; crotonase-like; 1.
DR InterPro; IPR029045; ClpP/crotonase-like_dom_sf.
DR InterPro; IPR045004; ECH_dom.
DR InterPro; IPR032259; HIBYL-CoA-H.
DR PANTHER; PTHR43176:SF3; 3-HYDROXYISOBUTYRYL-COA HYDROLASE, MITOCHONDRIAL; 1.
DR PANTHER; PTHR43176; 3-HYDROXYISOBUTYRYL-COA HYDROLASE-RELATED; 1.
DR Pfam; PF16113; ECH_2; 1.
DR SUPFAM; SSF52096; ClpP/crotonase; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000283090}.
FT DOMAIN 44..386
FT /note="Enoyl-CoA hydratase/isomerase"
FT /evidence="ECO:0000259|Pfam:PF16113"
SQ SEQUENCE 482 AA; 53605 MW; AEC6E67AFA6F3D8E CRC64;
MPLRARIGVN AMAQNSRSQS TAATAADEVE NTDDDVLFDS IKGVRTITLN RPKKLNALSA
SMAGKILPRL LEWQKSQMAN VIVIKGAGDR AFCAGGDVAV LAAQNRTGPE GQQASIDYFA
LEYKLDNLIA KYTKPYVAFM DGITMGGGVG LSLHGHFRIA TERTVFSMPE TTIGFFPDVG
ASFFLPRLDG YLGTYLALTS ERLGGVQAYW AGVATHYIHS SSLQDLQDRL AELEFNDHDD
LQWRLEHINS TIEEYTTGLP HNEPFKLGGE TRRAIDRCFR YNTIDEIMQA LRNEDSEWAN
QTIRTLRSRS PIALRVTLLE MRYGAAWTIN TAFMREFHMA QKFMNDTLHP DFVEGVEKQL
ARSLDGVKVP PSWKPSSIEE TTDAMALGYL EIEDGAQGLD LVKVPGEVDF ANYPHGWLGL
PSENAVRIML GKGGKKTIGE LEKAVLKQWD NKVGVQEKLR DVFERKIKEG PGGIAEWKVE
EA
//
