ID   A0A437A1P5_9PEZI        Unreviewed;       782 AA.
AC   A0A437A1P5;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   13-SEP-2023, entry version 15.
DE   RecName: Full=MutL C-terminal dimerisation domain-containing protein {ECO:0000259|SMART:SM00853};
GN   ORFNames=DFL_003379 {ECO:0000313|EMBL:RVD85048.1};
OS   Arthrobotrys flagrans.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC   Orbiliales; Orbiliaceae; Arthrobotrys.
OX   NCBI_TaxID=97331 {ECO:0000313|EMBL:RVD85048.1, ECO:0000313|Proteomes:UP000283090};
RN   [1] {ECO:0000313|EMBL:RVD85048.1, ECO:0000313|Proteomes:UP000283090}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CBS H-5679 {ECO:0000313|EMBL:RVD85048.1,
RC   ECO:0000313|Proteomes:UP000283090};
RA   Youssar L., Wernet V., Hensel N., Hildebrandt H.-G., Fischer R.;
RT   "Intercellular communication is required for trap formation in the
RT   nematode-trapping fungus Duddingtonia flagrans.";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC       {ECO:0000256|ARBA:ARBA00006082}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RVD85048.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; SAEB01000006; RVD85048.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A437A1P5; -.
DR   STRING; 97331.A0A437A1P5; -.
DR   VEuPathDB; FungiDB:DFL_003379; -.
DR   Proteomes; UP000283090; Unassembled WGS sequence.
DR   GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR   GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR   Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR   Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR   Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR   InterPro; IPR036890; HATPase_C_sf.
DR   InterPro; IPR038973; MutL/Mlh/Pms-like.
DR   InterPro; IPR014790; MutL_C.
DR   InterPro; IPR042120; MutL_C_dimsub.
DR   InterPro; IPR042121; MutL_C_regsub.
DR   InterPro; IPR037198; MutL_C_sf.
DR   PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR   PANTHER; PTHR10073:SF47; DNA MISMATCH REPAIR PROTEIN MLH3; 1.
DR   Pfam; PF13589; HATPase_c_3; 1.
DR   Pfam; PF08676; MutL_C; 1.
DR   SMART; SM00853; MutL_C; 1.
DR   SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR   SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000283090}.
FT   DOMAIN          556..724
FT                   /note="MutL C-terminal dimerisation"
FT                   /evidence="ECO:0000259|SMART:SM00853"
FT   REGION          431..453
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   782 AA;  86768 MW;  C5D641C235ECBFE5 CRC64;
     MDRQPRIQRL SANAIARIRS TVSLTSLAGA VQELLMNSID ANATTINIFI NIIKNSIIIE
     DDGDGIFPGD MTLVGNRYST SKSTYSPTFG SRGEFLSSLA TSSLLTIYSR SKFYRSTHAV
     RYHYGSRLVC GQIENDHLML PKSGTKAIVD RLFGNFPVRL VGREDMTATE IAKEWKDIGR
     KVVEVVLLCA KNGRGVKVVV RNEEGVRKAV FDIGSGDESD APVRVGNVVH QAGLGKIVWE
     NISGGWRGIT MKGVIGLVPA ADKERQFIFV NGSPVGRHTN SILYSKINSL FAASSFGTID
     ENVAPEVGKR WVVRKGVERH PSFVIFVETS GSLNTVHAED LEVDSGNTIL LDVTGLIEAV
     VDEFLRVGGW KKRVTAMPRR KVDEDVDAMP KWVPKRRADL ALDLVFPTRM KSSHSLAAQS
     FNGAKIRRVL PEPAERPPPG EQIQQESAPA NDPGVLRYLD PAMNKYVLLD ARTGNEIRTP
     KPQAMPKRLT LLPEQRKGSM NAQGWASNIV SSFKTPVYRN PEAQIPRKSM ISDTFKGDEY
     ISTARLSKSS LQTARVIAQV DEKFILLSFQ SPELLVIVDQ HAADERIRVE RLWKEFDNLP
     KPLKKEVSFS IGADEANIMR LYIDDMRSWG FELDITLIRG AHGAVTVDVV GAPELVADRC
     VSEPSVVVRL LRGWIAELKE EKRSRGFPDG RGGWIKRMVT ATQRLNEVVS SRACRSAIMF
     NDNLTLEECK ELIERLAACD FPFQCAHGRP SMVPVVDLVD DGIEARFNED YRTAAKYTAA
     DS
//