ID A0A437AGW4_9PEZI Unreviewed; 454 AA.
AC A0A437AGW4;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 17.
DE RecName: Full=poly(A)-specific ribonuclease {ECO:0000256|ARBA:ARBA00012161};
DE EC=3.1.13.4 {ECO:0000256|ARBA:ARBA00012161};
GN ORFNames=DFL_001282 {ECO:0000313|EMBL:RVD90308.1};
OS Arthrobotrys flagrans.
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Orbiliomycetes;
OC Orbiliales; Orbiliaceae; Arthrobotrys.
OX NCBI_TaxID=97331 {ECO:0000313|EMBL:RVD90308.1, ECO:0000313|Proteomes:UP000283090};
RN [1] {ECO:0000313|EMBL:RVD90308.1, ECO:0000313|Proteomes:UP000283090}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CBS H-5679 {ECO:0000313|EMBL:RVD90308.1,
RC ECO:0000313|Proteomes:UP000283090};
RA Youssar L., Wernet V., Hensel N., Hildebrandt H.-G., Fischer R.;
RT "Intercellular communication is required for trap formation in the
RT nematode-trapping fungus Duddingtonia flagrans.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Exonucleolytic cleavage of poly(A) to 5'-AMP.; EC=3.1.13.4;
CC Evidence={ECO:0000256|ARBA:ARBA00001663};
CC -!- SIMILARITY: Belongs to the CAF1 family.
CC {ECO:0000256|ARBA:ARBA00008372}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVD90308.1}.
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DR EMBL; SAEB01000001; RVD90308.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437AGW4; -.
DR STRING; 97331.A0A437AGW4; -.
DR VEuPathDB; FungiDB:DFL_001282; -.
DR Proteomes; UP000283090; Unassembled WGS sequence.
DR GO; GO:0030014; C:CCR4-NOT complex; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0004535; F:poly(A)-specific ribonuclease activity; IEA:UniProtKB-EC.
DR GO; GO:0006402; P:mRNA catabolic process; IEA:UniProt.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR039637; CNOT7/CNOT8/Pop2.
DR InterPro; IPR006941; RNase_CAF1.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR10797; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT; 1.
DR PANTHER; PTHR10797:SF0; CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 7; 1.
DR Pfam; PF04857; CAF1; 2.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000283090};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT REGION 1..97
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..454
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 39..97
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 392..442
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 454 AA; 50189 MW; 97528D602AF3709A CRC64;
MPPARGNAFG PPMHSSSPFG NQHLLHGNPH HGSHHLAHHQ MQPQHQQHIQ HQSHHQQHAQ
QSQHQQALQQ QVAHAQHAQQ QQQQQHSQQS LHSQAATQQQ QSLQQQAAAA AAAAIKEVWK
QNLESEIAVL RDLVEDYPYI AMDTEFPGIV ARPIGGFRSK ADYHYQTLRC NVDMLKIIQL
GITFYDENGK TPEPVSTWQF NFQFSLADDM YAQDSIDLLT KSGIDFKRHE DHGIDVAQFG
ELLISSGLVL LDNVKWVSFH SGYDFGYLVK IMLCQALPAE ENEFRKYLHT FFPALYDIKY
LMKSVKTLKG GLQDIAEDMG VQRVGPQHQA GSDSLLTGHI FFAMKGKYFE GKIDEEKYCG
QVWGLNGVGN SGPTLNTTGA VQYTNGQTGV QNGGHIPSTP TNAGPSVPST GMTPGPMTPQ
QQINPYAQPP PQNSQQGVNP MGSGGFQFGK IGGL
//
