ID A0A437D713_ORYJA Unreviewed; 879 AA.
AC A0A437D713;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=FERM domain-containing protein {ECO:0000259|PROSITE:PS50057};
GN ORFNames=OJAV_G00064100 {ECO:0000313|EMBL:RVE70389.1};
OS Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC Oryzias.
OX NCBI_TaxID=123683 {ECO:0000313|EMBL:RVE70389.1, ECO:0000313|Proteomes:UP000283210};
RN [1] {ECO:0000313|EMBL:RVE70389.1, ECO:0000313|Proteomes:UP000283210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS831 {ECO:0000313|EMBL:RVE70389.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RVE70389.1};
RA Lopez-Roques C., Donnadieu C., Bouchez O., Klopp C., Cabau C., Zahm M.;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:RVE70389.1, ECO:0000313|Proteomes:UP000283210}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RS831 {ECO:0000313|EMBL:RVE70389.1};
RC TISSUE=Whole body {ECO:0000313|EMBL:RVE70389.1};
RA Herpin A., Takehana Y., Naruse K., Ansai S., Kawaguchi M.;
RT "A chromosome length genome reference of the Java medaka (oryzias
RT javanicus).";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; CM012443; RVE70389.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437D713; -.
DR Ensembl; ENSOJAT00000044497; ENSOJAP00000041745; ENSOJAG00000020362.
DR Proteomes; UP000283210; Chromosome 7.
DR GO; GO:0005856; C:cytoskeleton; IEA:InterPro.
DR GO; GO:0003779; F:actin binding; IEA:InterPro.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR GO; GO:0030866; P:cortical actin cytoskeleton organization; IEA:InterPro.
DR CDD; cd14473; FERM_B-lobe; 1.
DR CDD; cd13184; FERM_C_4_1_family; 1.
DR Gene3D; 1.20.80.10; -; 1.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR008379; Band_4.1_C.
DR InterPro; IPR019749; Band_41_domain.
DR InterPro; IPR000798; Ez/rad/moesin-like.
DR InterPro; IPR014847; FA.
DR InterPro; IPR014352; FERM/acyl-CoA-bd_prot_sf.
DR InterPro; IPR035963; FERM_2.
DR InterPro; IPR019748; FERM_central.
DR InterPro; IPR019747; FERM_CS.
DR InterPro; IPR000299; FERM_domain.
DR InterPro; IPR018979; FERM_N.
DR InterPro; IPR018980; FERM_PH-like_C.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR007477; SAB_dom.
DR InterPro; IPR029071; Ubiquitin-like_domsf.
DR PANTHER; PTHR23280; 4.1 G PROTEIN; 1.
DR PANTHER; PTHR23280:SF24; BAND 4.1-LIKE PROTEIN 1; 1.
DR Pfam; PF05902; 4_1_CTD; 1.
DR Pfam; PF08736; FA; 1.
DR Pfam; PF09380; FERM_C; 1.
DR Pfam; PF00373; FERM_M; 1.
DR Pfam; PF09379; FERM_N; 1.
DR Pfam; PF04382; SAB; 1.
DR PIRSF; PIRSF002304; Membrane_skeletal_4_1; 1.
DR PRINTS; PR00935; BAND41.
DR PRINTS; PR00661; ERMFAMILY.
DR SMART; SM00295; B41; 1.
DR SMART; SM01195; FA; 1.
DR SMART; SM01196; FERM_C; 1.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF47031; Second domain of FERM; 1.
DR SUPFAM; SSF54236; Ubiquitin-like; 1.
DR PROSITE; PS00660; FERM_1; 1.
DR PROSITE; PS00661; FERM_2; 1.
DR PROSITE; PS50057; FERM_3; 1.
PE 4: Predicted;
KW Actin-binding {ECO:0000256|ARBA:ARBA00023203};
KW Reference proteome {ECO:0000313|Proteomes:UP000283210}.
FT DOMAIN 57..338
FT /note="FERM"
FT /evidence="ECO:0000259|PROSITE:PS50057"
FT REGION 1..49
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 393..422
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 446..466
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 509..576
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 649..733
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..40
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 551..576
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 652..668
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 678..693
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 702..717
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 879 AA; 98479 MW; 58E27714A1DA78C1 CRC64;
MTTEAALSGE MKTAMEADIR KTSQVQEDHG ELDDSSEKTP SKASKSPQKT IKRLKTVPVK
VTLLDGSEYN TAVEKFAKGQ TLLDMVCGHL NLLERDYFGL NFVDTDNSKN WLDPSKEIKK
QIRVGFWSLG FSVKFYPPDP SVLIEDITRY YLCLQLRDDI LSGRLPCSFV THALLGSYTV
QAELGDYDPE EHGPDYVSEF HFAPNQTREL EERVMELHRN YRGMSPAEAE MNFLENAKKL
SMYGVDLHHA KDSEGIDIML GVSANGLLIY RDRLRINRFA WPKILKISYK RSNFYIKIRP
GEYEQFESTI GFKLPNHRAS KRLWKVCIEH HTFFRLVSPE PPPKGFLVIG SKFRYSGRTQ
AQTRQASALI DRPAPQFERS VSKRYMLPRS IDGASALGDS MDQLSQRSSS ERTQFMSRED
LDQEGSLDLE HDHYQYQDKD HDQYADLEDE HEEHSQKQTF GGRIPTPTKA LEVKGEEAGS
PVDPKQEQFL DKPEDVLQKH QASINELKRA LKQPNSKMAQ RERLSSATPP GGGTPERKSE
TPPTPTIHEE PLCEASREPW ERRLGSVSED DQDHDLPYLR ETHLGIERKC SSITVSSTSS
LEAEVDFTVL TDLQTGMEEF SRGMSELGER DLSPDGGLCM GIDLLQHQHV SEPPPPVVPT
PLPRGSTSSP PAKPVQTEEV RPEVKRPEGQ PVVPKKPKRS VPVSSSVDRD HPHKDAGRMA
AAAPLSREPS DVIPTPAVRK TDVRTETQPN GSEVTTTIVE FTDQDHAITG LGEISYSTRQ
SVSPVHKGTY GRETPGSPIL VTENVTSATT HVSKTVKGGY SETRIEKRII ITGDDDVDQE
QALAIAIQEA KQQHPDMQVT KAVVVRETES SVGERHGAS
//
