ID   A0A437DIN4_ORYJA        Unreviewed;       593 AA.
AC   A0A437DIN4;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   27-MAR-2024, entry version 15.
DE   RecName: Full=Protein phosphatase 1G {ECO:0000256|ARBA:ARBA00040767};
GN   ORFNames=OJAV_G00024210 {ECO:0000313|EMBL:RVE74642.1};
OS   Oryzias javanicus (Javanese ricefish) (Aplocheilus javanicus).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Atherinomorphae; Beloniformes; Adrianichthyidae; Oryziinae;
OC   Oryzias.
OX   NCBI_TaxID=123683 {ECO:0000313|EMBL:RVE74642.1, ECO:0000313|Proteomes:UP000283210};
RN   [1] {ECO:0000313|EMBL:RVE74642.1, ECO:0000313|Proteomes:UP000283210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS831 {ECO:0000313|EMBL:RVE74642.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:RVE74642.1};
RA   Lopez-Roques C., Donnadieu C., Bouchez O., Klopp C., Cabau C., Zahm M.;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|EMBL:RVE74642.1, ECO:0000313|Proteomes:UP000283210}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RS831 {ECO:0000313|EMBL:RVE74642.1};
RC   TISSUE=Whole body {ECO:0000313|EMBL:RVE74642.1};
RA   Herpin A., Takehana Y., Naruse K., Ansai S., Kawaguchi M.;
RT   "A chromosome length genome reference of the Java medaka (oryzias
RT   javanicus).";
RL   Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|ARBA:ARBA00001946};
CC   -!- COFACTOR:
CC       Name=Mn(2+); Xref=ChEBI:CHEBI:29035;
CC         Evidence={ECO:0000256|ARBA:ARBA00001936};
CC   -!- SUBUNIT: Interacts with NOL3; may dephosphorylate NOL3.
CC       {ECO:0000256|ARBA:ARBA00038798}.
CC   -!- SIMILARITY: Belongs to the PP2C family.
CC       {ECO:0000256|RuleBase:RU003465}.
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DR   EMBL; CM012439; RVE74642.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A437DIN4; -.
DR   Proteomes; UP000283210; Chromosome 3.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
DR   CDD; cd00143; PP2Cc; 2.
DR   Gene3D; 3.60.40.10; PPM-type phosphatase domain; 2.
DR   InterPro; IPR015655; PP2C.
DR   InterPro; IPR000222; PP2C_BS.
DR   InterPro; IPR036457; PPM-type-like_dom_sf.
DR   InterPro; IPR001932; PPM-type_phosphatase-like_dom.
DR   PANTHER; PTHR13832:SF876; PROTEIN PHOSPHATASE 1G; 1.
DR   PANTHER; PTHR13832; PROTEIN PHOSPHATASE 2C; 1.
DR   Pfam; PF00481; PP2C; 2.
DR   SMART; SM00332; PP2Cc; 1.
DR   SUPFAM; SSF81606; PP2C-like; 1.
DR   PROSITE; PS01032; PPM_1; 1.
DR   PROSITE; PS51746; PPM_2; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU003465};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Protein phosphatase {ECO:0000256|ARBA:ARBA00022912,
KW   ECO:0000256|RuleBase:RU003465};
KW   Reference proteome {ECO:0000313|Proteomes:UP000283210}.
FT   DOMAIN          57..556
FT                   /note="PPM-type phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS51746"
FT   REGION          209..380
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          561..593
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..256
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..367
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        562..593
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   593 AA;  64491 MW;  D0BA52B0547B6124 CRC64;
     MFNSSFLVTE FRLQWLLHRH PLVESRTFEK ATPSMGAYLS QPNTTKTSSD GGNSKMSYGF
     SAMQGWRVSM EDSHNCIPDF DEDTAMFSVY DGHGGEEVAL YCSKYLPDII KEQKTYKDGK
     LQKALEDAFL AIDGRITTAE VIKELVQISG RLSEDPPAEK VAEEDDLDTE EAALLHEEAT
     MTIEELLVRY GQNLNAVKHA AAISAAAKKA SSEDAEGAGQ KEEGEEKEKK DGLNGEVGEG
     SNKKVKEGDG VTRGAKLRAC RRTAGGEGNS AAATGKSESS NGEEKAGKTE GDAGPSCSSA
     SSKTPGDSKS RFFDDSEESE EGEEEEASDE EDGSEEEEGD SSELEEEDTE EGEEDSEDEE
     EEEMCLPGMD GKEEPGSDSG TTAVVALIRG KQLIVANAGD SRCVVSERGK AVDMSYDHKP
     EDEVELARIK NAGGKVTMDG RVNGGLNLSR AIGDHFYKRN DALPPEEQMI SAMPDVKVLT
     LNEDHDFMVI ACDGIWNVLS SQEVVDFISE RLKPDENDES RPLSSIVEEL LDHCLAPDTS
     GDGTGCDNMT CIIVTFQPHL TSSEDTKKRK IREEAEETET DKNDNDGKKA KLD
//