ID A0A437J6E8_9SPHN Unreviewed; 371 AA.
AC A0A437J6E8;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 24-JAN-2024, entry version 10.
DE RecName: Full=UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) {ECO:0000256|ARBA:ARBA00038858};
DE EC=5.1.3.14 {ECO:0000256|ARBA:ARBA00038858};
GN ORFNames=ENE74_09720 {ECO:0000313|EMBL:RVT40751.1};
OS Sphingobium algorifonticola.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingobium.
OX NCBI_TaxID=2008318 {ECO:0000313|EMBL:RVT40751.1, ECO:0000313|Proteomes:UP000282977};
RN [1] {ECO:0000313|EMBL:RVT40751.1, ECO:0000313|Proteomes:UP000282977}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TLA-22 {ECO:0000313|EMBL:RVT40751.1,
RC ECO:0000313|Proteomes:UP000282977};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=UDP-N-acetyl-alpha-D-glucosamine = UDP-N-acetyl-alpha-D-
CC mannosamine; Xref=Rhea:RHEA:17213, ChEBI:CHEBI:57705,
CC ChEBI:CHEBI:68623; EC=5.1.3.14;
CC Evidence={ECO:0000256|ARBA:ARBA00036080};
CC -!- SIMILARITY: Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
CC {ECO:0000256|ARBA:ARBA00038209, ECO:0000256|RuleBase:RU003513}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVT40751.1}.
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DR EMBL; RZUL01000003; RVT40751.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437J6E8; -.
DR OrthoDB; 9803238at2; -.
DR Proteomes; UP000282977; Unassembled WGS sequence.
DR GO; GO:0008761; F:UDP-N-acetylglucosamine 2-epimerase activity; IEA:UniProtKB-EC.
DR CDD; cd03786; GTB_UDP-GlcNAc_2-Epimerase; 1.
DR Gene3D; 3.40.50.2000; Glycogen Phosphorylase B; 2.
DR InterPro; IPR003331; UDP_GlcNAc_Epimerase_2_dom.
DR InterPro; IPR029767; WecB-like.
DR NCBIfam; TIGR00236; wecB; 1.
DR PANTHER; PTHR43174; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR PANTHER; PTHR43174:SF2; UDP-N-ACETYLGLUCOSAMINE 2-EPIMERASE; 1.
DR Pfam; PF02350; Epimerase_2; 1.
DR SUPFAM; SSF53756; UDP-Glycosyltransferase/glycogen phosphorylase; 1.
PE 3: Inferred from homology;
KW Isomerase {ECO:0000256|ARBA:ARBA00023235, ECO:0000256|RuleBase:RU003513};
KW Reference proteome {ECO:0000313|Proteomes:UP000282977}.
FT DOMAIN 22..367
FT /note="UDP-N-acetylglucosamine 2-epimerase"
FT /evidence="ECO:0000259|Pfam:PF02350"
SQ SEQUENCE 371 AA; 39532 MW; B6E2122DA3C50654 CRC64;
MKILCVFGTR PEAIKLFPVI HALRAAPGID VRVCVTAQHR GLLDQVLEIA GIVPDIDLDV
MTPNQTLDGL TATLIVQLGK AFDAEQPDRV LVHGDTLTTM VASLAAYYRK IPVAHVEAGL
RSGDIHHPWP EEVNRRVVAC IADMNFAPTQ GAADALLAEG RDPAGIHVTG NTVIDALLAT
KARIDAEPGL ACGLDDLATR FAGRRIVAVT SHRRENFGGG MDAIAGAVRD IAARADVAVI
FPVHPNPNVR RVMDAALADL PHVALIDPLD YPHFVRLLDI CYLVLTDSGG VQEEAPSLGK
PVLVMRETTE RPEGIAAGTA KLVGTDRARI VAEVFALLND EAAYAEMARA HNPFGDGRAS
GRIARIIGGD I
//
