ID A0A437K1Z7_9BURK Unreviewed; 2738 AA.
AC A0A437K1Z7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=SDR family NAD(P)-dependent oxidoreductase {ECO:0000313|EMBL:RVT54369.1};
GN ORFNames=ENE75_05860 {ECO:0000313|EMBL:RVT54369.1};
OS Rubrivivax albus.
OC Bacteria; Pseudomonadota; Betaproteobacteria; Burkholderiales;
OC Sphaerotilaceae; Rubrivivax.
OX NCBI_TaxID=2499835 {ECO:0000313|EMBL:RVT54369.1, ECO:0000313|Proteomes:UP000288178};
RN [1] {ECO:0000313|EMBL:RVT54369.1, ECO:0000313|Proteomes:UP000288178}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ICH-3 {ECO:0000313|EMBL:RVT54369.1,
RC ECO:0000313|Proteomes:UP000288178};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVT54369.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SACT01000001; RVT54369.1; -; Genomic_DNA.
DR OrthoDB; 9778690at2; -.
DR Proteomes; UP000288178; Unassembled WGS sequence.
DR GO; GO:0004315; F:3-oxoacyl-[acyl-carrier-protein] synthase activity; IEA:InterPro.
DR GO; GO:0018580; F:nitronate monooxygenase activity; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR CDD; cd00833; PKS; 1.
DR Gene3D; 3.40.47.10; -; 1.
DR Gene3D; 1.10.1200.10; ACP-like; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 2.
DR Gene3D; 3.30.70.250; Malonyl-CoA ACP transacylase, ACP-binding; 1.
DR Gene3D; 3.40.366.10; Malonyl-Coenzyme A Acyl Carrier Protein, domain 2; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR Gene3D; 3.10.129.110; Polyketide synthase dehydratase; 1.
DR InterPro; IPR001227; Ac_transferase_dom_sf.
DR InterPro; IPR036736; ACP-like_sf.
DR InterPro; IPR014043; Acyl_transferase.
DR InterPro; IPR016035; Acyl_Trfase/lysoPLipase.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR018201; Ketoacyl_synth_AS.
DR InterPro; IPR014031; Ketoacyl_synth_C.
DR InterPro; IPR014030; Ketoacyl_synth_N.
DR InterPro; IPR016036; Malonyl_transacylase_ACP-bd.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR004136; NMO.
DR InterPro; IPR020841; PKS_Beta-ketoAc_synthase_dom.
DR InterPro; IPR042104; PKS_dehydratase_sf.
DR InterPro; IPR020807; PKS_DH.
DR InterPro; IPR049551; PKS_DH_C.
DR InterPro; IPR049552; PKS_DH_N.
DR InterPro; IPR013968; PKS_KR.
DR InterPro; IPR009081; PP-bd_ACP.
DR InterPro; IPR016039; Thiolase-like.
DR PANTHER; PTHR43074; OMEGA-3 POLYUNSATURATED FATTY ACID SYNTHASE PFAB-RELATED; 1.
DR PANTHER; PTHR43074:SF1; PKS_AT DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00698; Acyl_transf_1; 1.
DR Pfam; PF00109; ketoacyl-synt; 1.
DR Pfam; PF02801; Ketoacyl-synt_C; 1.
DR Pfam; PF08659; KR; 1.
DR Pfam; PF03060; NMO; 1.
DR Pfam; PF21089; PKS_DH_N; 1.
DR Pfam; PF00550; PP-binding; 1.
DR Pfam; PF14765; PS-DH; 1.
DR SMART; SM00827; PKS_AT; 1.
DR SMART; SM00826; PKS_DH; 1.
DR SMART; SM00822; PKS_KR; 1.
DR SMART; SM00825; PKS_KS; 1.
DR SUPFAM; SSF47336; ACP-like; 1.
DR SUPFAM; SSF52151; FabD/lysophospholipase-like; 1.
DR SUPFAM; SSF51412; Inosine monophosphate dehydrogenase (IMPDH); 2.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 2.
DR SUPFAM; SSF55048; Probable ACP-binding domain of malonyl-CoA ACP transacylase; 1.
DR SUPFAM; SSF53901; Thiolase-like; 1.
DR PROSITE; PS50075; CARRIER; 1.
DR PROSITE; PS00606; KS3_1; 1.
DR PROSITE; PS52004; KS3_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000288178};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 683..1125
FT /note="Ketosynthase family 3 (KS3)"
FT /evidence="ECO:0000259|PROSITE:PS52004"
FT DOMAIN 1803..1887
FT /note="Carrier"
FT /evidence="ECO:0000259|PROSITE:PS50075"
FT REGION 1631..1694
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2738 AA; 287532 MW; DC47B00C1FB28C23 CRC64;
MNAFTTFVFT PAGLGHADLA IAASRAGAVG IYNAEFDDGT AAARQALARL AQLGRGDIGL
KLDAIDDALA SDVAVLAARR GGLWMVVDLP LLATHAGVVA GWRQAGVRVL AEVRHATALP
AGAEAQIDGL VVKGNEAPGL VGEDASFILL QKWLRATQLP LVLRGGLTPA VAAAIHAVGA
AGGVLESQLL LLDEVCLPDL LRQTLGSLSG SETVAVGDGE AGDYLRVLVR PAFAAARRFV
TEGEGLRADA LRARMVGHAG WQSPAEGLLP IGQEVVFAAA WRRRHGSLAG ILGAIRQAID
AQPALARAQP VLREHGPLAE ALGIRYPVVQ GPMTRVSDSA EFARAVAEGG ALPMIAFAML
KGQALEQLLV RTTELLGDRA WGIGLLGFAP QALLDEQLAI ATRFGPRYAI IAGGRPDQAV
HLERAGVATY LHVPSANLIP GFLAEGARRF IFEGRECGGH IGPLSSFVLW STMVDKLTDE
LGTGKVPAAD VELLFAGGVH DALSSAMLQV LVAPLAAAGA RVGVLMGSAY LFTREIVDSG
AIVEPFQQAV IACDHTVNLE SGPGHASRCA YTPFAADFFR ERQRLKREGV PGDESRRVLD
DLILGRLRIA SKGTKREGLN APLQRLDPQQ QLAEGMYMLG QVATLRSAVT DIASLHAEVT
DGAAALLATD EVLPAATEPA LPPADIAIIG VACVVPQAND APAFWQNILE RVDAITEIPS
HRWDWRLYFD PDRKAKDKVY SKWGGFLDDL PFDPTRYGMP PKSIQAVDPM QLMGLEVARR
TLADAGYADR AFDRERASVI VGASGGAGDY GLQYGLRSEL PRFTGDLPAE VAARLPEWSE
DSFAGILPNV VAGRIANRLN FGGINLAVDA ACASSLAAVY QGVTELVAGR SDLVIAGGVD
TVQGPFGYLC FSKTQALSPR GRCSTFDAEG DGIVISEGIA MVALKRLADA ERDGDRIYAV
IKGVGASSDG NAKGLTAPLP AGQLRAMRRA YRMAGFGPST VGLFEAHGTG TVAGDTAELE
STTRLIREEG ARPRQAVIGS VKTNIGHTKA TAGVAGMVKA ALALRHRVLP PHRNVQRPNA
VLADPDAPLY LLEAPMPWLA GVHPRRAACS AFGFGGTNFH VVLEEYAGEY RDWLRAPAAD
RWSAELLLWS EADAEALAAR LEALQPRLAA VSGIELRDLA ASLAARFQPR GRTAAIVARS
VEDLGSKLAA AVAKLRGDAR PLPPGVHLGE GTTPAGKVAV LFSGQGSQYP DMLREPALHF
EALRSALEEA DEALAADFAE RFGAGTRLSE FVFPRGAYDD ATKDAARRRL TGTDVAQPAL
GAIEVGLWRL LRGLGLPVDM VAGHSYGEFV ALHAAGAIDF ASLMQLSAAR GRFIVDAAKA
EGAELGTMAA VSAPRKDVED AIADLEGVII ANHNAPTQSI LSGTREAVQA ASAKLQQAGL
EVTPIPVAAA FHSVLVRPAQ AALSAQIEAT PWAPAMLPVY SNTTARPHAA DVVRVKKQMA
EHLVRPVEWV AEVEAMADDG ATLFVELGPK AVLARLAGRI LHGRPHLAVA MDDGSGLPGL
LSGLAQLVCA GVPLAVTKLF EGRDCRLGDP ADPVALRLPT PVSPHAWMLN GSGARRASEP
VRQIGVTLEQ AASVPPPAQP AAMPATSALP PSAMPTASAP AASPALSPVT PPWRKGRSMD
ERRHPSGPAD PSVMSDYFAT MRQFLETQER VMASFLGADM APARPALRMS RAITAALPRV
AEVPAPAVVV PPVPAVQAPV ASAPVTVAPA PAPAAVAPVP VAPVPTAPAP VAAPAPAAAG
EGLTRAKLVD LLLAIVEDKT GYPRDMVGLD QNLEADLGID SIKRIEVVGA LLQQLPAAHR
DALTDKRSQL NTQSTLNGML DLVAAAEVGG AVAVPFDRAG GESRVDDRTA VAGHPPRQVM
QAVAEPIPAG AGTVLAAGRY VLTRDTAGVA DALAGLLQAQ GRSVAIVDAN LADEAALDAW
AQALGDAPAA GVLHLAALAS PGLGDSPDGW RSALLRHEKS LFLLLNRLDG RLAADGHVLA
ATDLGGLFGR DGTLGQGLRL VGGAVGALKS YGEERPTLRV KAVDLDPAQP ADAQARALFD
ELRLDGGRQE VGYPGGLRTT FRSVGVAVTA DPSREAALHD LVVLATGGAR GITAEVLREL
AAPGSTLVLT GRSRLVEVEA ADTAACADAA ALRQHFVAQV RAGALKLTPG EIQRQVQGVL
DQREMRANLE ALRAAGATVE YHPVDVTDAV AVAALVADVV HRHGRVDGVV HGAGVIEDKR
LADKRGDSWS RVVETKVLGL LALVQALGAK APKFFAAFSS VAGRYGNSGQ SDYATANELM
NRLCTALQAR WGKDTVVSAM CWGPWGPTST GAGMVTAETE AKFAAKGVRL VSASLGRRLF
RSELARAAGG AVEVVFGEAD WERHEAAKGV IRRAPALAPL LGATEPSSLP TGERLVPVRL
DPTRHLYLQE HALDNRYVLP AAAALEIVAE AAAALWPGWK VTEVHEHRLM KGVELDAAGR
ALRVFLSPPP YGSSEGFEVS AQLQSEIAPD RWLTHYRATV RLEQVWPAPA PMPRVHHGER
TLSTAQAYGE WLFHGPRFQV ITAFDGLSAQ GAAAQVVSTH PSRWLAHEAA DGPGWVFDPA
LLDAAAQMAW LWARAFRDES ALPARFGRVV RYRDRLPERL HMEYQRVAAE DPTLVRGHVT
FFDADGVPVL AVEELDSIAS AALNRLGGTA RTAEEPAS
//
