ID A0A437Q7P1_9GAMM Unreviewed; 530 AA.
AC A0A437Q7P1;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 15.
DE RecName: Full=histidine kinase {ECO:0000256|ARBA:ARBA00012438};
DE EC=2.7.13.3 {ECO:0000256|ARBA:ARBA00012438};
GN ORFNames=EOE65_09570 {ECO:0000313|EMBL:RVU30562.1};
OS Neptunomonas marina.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Neptunomonas.
OX NCBI_TaxID=1815562 {ECO:0000313|EMBL:RVU30562.1, ECO:0000313|Proteomes:UP000282818};
RN [1] {ECO:0000313|EMBL:RVU30562.1, ECO:0000313|Proteomes:UP000282818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPM-16 {ECO:0000313|EMBL:RVU30562.1,
RC ECO:0000313|Proteomes:UP000282818};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + protein L-histidine = ADP + protein N-phospho-L-
CC histidine.; EC=2.7.13.3; Evidence={ECO:0000256|ARBA:ARBA00000085};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVU30562.1}.
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DR EMBL; SACQ01000004; RVU30562.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437Q7P1; -.
DR Proteomes; UP000282818; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR CDD; cd16922; HATPase_EvgS-ArcB-TorS-like; 1.
DR CDD; cd00082; HisKA; 1.
DR Gene3D; 1.10.287.130; -; 1.
DR Gene3D; 6.10.340.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR003660; HAMP_dom.
DR InterPro; IPR003594; HATPase_C.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR005467; His_kinase_dom.
DR InterPro; IPR003661; HisK_dim/P.
DR InterPro; IPR036097; HisK_dim/P_sf.
DR InterPro; IPR019247; Histidine_kinase_BarA_N.
DR InterPro; IPR004358; Sig_transdc_His_kin-like_C.
DR PANTHER; PTHR43711:SF1; HISTIDINE KINASE 1; 1.
DR PANTHER; PTHR43711; TWO-COMPONENT HISTIDINE KINASE; 1.
DR Pfam; PF00672; HAMP; 1.
DR Pfam; PF02518; HATPase_c; 1.
DR Pfam; PF00512; HisKA; 1.
DR Pfam; PF09984; sCache_4; 1.
DR PRINTS; PR00344; BCTRLSENSOR.
DR SMART; SM00304; HAMP; 1.
DR SMART; SM00387; HATPase_c; 1.
DR SMART; SM00388; HisKA; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF47384; Homodimeric domain of signal transducing histidine kinase; 1.
DR PROSITE; PS50885; HAMP; 1.
DR PROSITE; PS50109; HIS_KIN; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Kinase {ECO:0000256|ARBA:ARBA00022777}; Membrane {ECO:0000256|SAM:Phobius};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Reference proteome {ECO:0000313|Proteomes:UP000282818};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 180..203
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 204..256
FT /note="HAMP"
FT /evidence="ECO:0000259|PROSITE:PS50885"
FT DOMAIN 296..514
FT /note="Histidine kinase"
FT /evidence="ECO:0000259|PROSITE:PS50109"
FT COILED 241..271
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 530 AA; 58216 MW; ECB36731783FA052 CRC64;
MNQMINNKNY SFRRQLMIFL IAAIALLSLV SSTVSSWIAL HQSGQVLEKN ALQIADHFSK
QSVLALLTRS EDNAESALSQ VMGFADVTGG AIFADTQQAL FVKGEIQPDQ AKLADWLSSP
KPIIAVDARD YWIITSPVIL EDDRETFTEF ALSQTHTQQL LGFVMIQVSK SSIVQLTQQL
FSYTIGIGIV FALLCLWLLN IGLRRIIDPI RALSATMKAA QDSGAHTYAE ISGPQEVHSI
AQSYNAMMAA LEAQEKRLKE LNTSLESEVE IRTKELTHAR DTALVAVRTQ SEFLANISHE
LRTPLQAVMG YIDLVVEELN EQGMYDQVSD LEASLSAANR LLTLINSILD LAKCEAGKTE
LVLTETPLKR LIKETEAIIR PLAVRNSNTL TIHLPDSDSI LLIDKEKTQQ ILLNLLSNAC
KFTKAGTVEL HIDLQDETVK FAVSDTGVGI AADKLESIFD KFSQGDGSVK RRYGGTGLGL
AISKHFAEMM NGSIHVSSAQ EQGSLFTLTL PKQVTFKNSL TMGSSEDQKG
//
