ID A0A437QAI7_9GAMM Unreviewed; 956 AA.
AC A0A437QAI7;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 13.
DE SubName: Full=EAL domain-containing protein {ECO:0000313|EMBL:RVU31419.1};
GN ORFNames=EOE65_05390 {ECO:0000313|EMBL:RVU31419.1};
OS Neptunomonas marina.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Oceanospirillales;
OC Oceanospirillaceae; Neptunomonas.
OX NCBI_TaxID=1815562 {ECO:0000313|EMBL:RVU31419.1, ECO:0000313|Proteomes:UP000282818};
RN [1] {ECO:0000313|EMBL:RVU31419.1, ECO:0000313|Proteomes:UP000282818}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HPM-16 {ECO:0000313|EMBL:RVU31419.1,
RC ECO:0000313|Proteomes:UP000282818};
RA Chen W.-M.;
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVU31419.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; SACQ01000002; RVU31419.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437QAI7; -.
DR Proteomes; UP000282818; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR CDD; cd01948; EAL; 1.
DR CDD; cd01949; GGDEF; 1.
DR CDD; cd00130; PAS; 1.
DR CDD; cd18774; PDC2_HK_sensor; 1.
DR Gene3D; 3.30.70.270; -; 1.
DR Gene3D; 3.20.20.450; EAL domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 3.
DR InterPro; IPR004010; Double_Cache_2.
DR InterPro; IPR001633; EAL_dom.
DR InterPro; IPR035919; EAL_sf.
DR InterPro; IPR000160; GGDEF_dom.
DR InterPro; IPR029787; Nucleotide_cyclase.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR000700; PAS-assoc_C.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR InterPro; IPR033480; sCache_2.
DR NCBIfam; TIGR00254; GGDEF; 1.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR44757:SF2; BIOFILM ARCHITECTURE MAINTENANCE PROTEIN MBAA; 1.
DR PANTHER; PTHR44757; DIGUANYLATE CYCLASE DGCP; 1.
DR Pfam; PF08269; dCache_2; 1.
DR Pfam; PF00563; EAL; 1.
DR Pfam; PF00990; GGDEF; 1.
DR Pfam; PF13426; PAS_9; 1.
DR SMART; SM01049; Cache_2; 1.
DR SMART; SM00052; EAL; 1.
DR SMART; SM00267; GGDEF; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 1.
DR SUPFAM; SSF141868; EAL domain-like; 1.
DR SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 1.
DR PROSITE; PS50883; EAL; 1.
DR PROSITE; PS50887; GGDEF; 1.
DR PROSITE; PS50113; PAC; 1.
DR PROSITE; PS50112; PAS; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000282818};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 12..34
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 403..449
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 476..528
FT /note="PAC"
FT /evidence="ECO:0000259|PROSITE:PS50113"
FT DOMAIN 561..695
FT /note="GGDEF"
FT /evidence="ECO:0000259|PROSITE:PS50887"
FT DOMAIN 704..956
FT /note="EAL"
FT /evidence="ECO:0000259|PROSITE:PS50883"
SQ SEQUENCE 956 AA; 108689 MW; 0DC3910B284B2409 CRC64;
MSLNIDTQSI PRYLTAGMLG AVLLLLATTI VFFFSRLYDD TSRLEELHVD VVEAQKKRLT
HELNSLHDYI RFTSTQAEME LEQQSKEVVD LAYHLAHSLY QQNQQRLTEA QLKTQIIEAL
RGPRFFSGRG YYFIDDMAGQ CILLPTAPDL EGSSLLDNRD DTGHYIMRGL IDVVEQSETH
SGYSRYRWYA PDYPDQMRNK IAYVRLFEPY GWIIGAGDYL YQFENDLKEI ALTRIRSLRF
GDNGYFSVLD REGNVLYAPK SSAQFPVHVD NIPSKMERDV VHKVLAVAEQ GGGFVQYDWF
TPNTDEPRIA RKLSLVQNVD EWGWVLVAGV YPEEIEAVYR DLVLRQKEND RRDFIKLVIA
LSVIGAGVLV CAWLYGSWLK RLFYAYQKSI ETQQSKIEGD AKALRIASRV FDTASEGIIV
TNPDNQIVAV NRSFTAITGY QEEEVVGRSP SILSSGKHTR EFYDSMWRVL QDEGRWAGEI
WNRTKSGAVY PEQLSIAVSR DEDGNVVNYI ATFSDVSDQK KAEEQLRYMA DYDELTGLPN
RRHLMAQVAR LINEVDQGEL HQFHLLFMDL DRFKVINDSL GHWVGDKVLQ EIAQRLRQDV
VDIDMIGRLG GDEFVILLRE QPEVTESAGT YAQRLIQVVA EAIKDKDFDL VVTPSIGIAS
YPDDGADFGA LLSSADAALY HAKSQGRNNY QFYRRDLNAK ASRRLLMESA LRMALERDEL
ELYYQPQYNL LDRSIVGCEA LLRWKHDGQF ISPAEFIPLA EDSGLILSIG DWVLEEGCRQ
GAEWLKQGFD LPCVAINVSP VQFREGFFET VMDILERTGF PASHLELELT ESTLMNDVNR
AQQLLSSFRA IGVRTALDDF GTGYSSLAYL KKFSLDKLKI DRAFIDGLPD DSDDNAITAS
ILDVARHLSL ETIAEGVETE AQLNFLGAYG CDQVQGFYFS KPLTSQDFVR LLHKVH
//
