ID A0A437QL54_9PROT Unreviewed; 374 AA.
AC A0A437QL54;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=succinyl-diaminopimelate desuccinylase {ECO:0000256|ARBA:ARBA00011921};
DE EC=3.5.1.18 {ECO:0000256|ARBA:ARBA00011921};
GN Name=argE {ECO:0000313|EMBL:RVU35244.1};
GN ORFNames=EOI86_20760 {ECO:0000313|EMBL:RVU35244.1};
OS Hwanghaeella grinnelliae.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC Rhodospirillaceae; Hwanghaeella.
OX NCBI_TaxID=2500179 {ECO:0000313|EMBL:RVU35244.1, ECO:0000313|Proteomes:UP000287447};
RN [1] {ECO:0000313|Proteomes:UP000287447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Gri0909 {ECO:0000313|Proteomes:UP000287447};
RA Kim J., Jeong S.E., Jeon C.O.;
RT "Gri0909 isolated from a small marine red alga.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=H2O + N-succinyl-(2S,6S)-2,6-diaminoheptanedioate =
CC (2S,6S)-2,6-diaminoheptanedioate + succinate; Xref=Rhea:RHEA:22608,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:30031, ChEBI:CHEBI:57609,
CC ChEBI:CHEBI:58087; EC=3.5.1.18;
CC Evidence={ECO:0000256|ARBA:ARBA00001246};
CC -!- COFACTOR:
CC Name=Co(2+); Xref=ChEBI:CHEBI:48828;
CC Evidence={ECO:0000256|ARBA:ARBA00001941};
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- PATHWAY: Amino-acid biosynthesis; L-lysine biosynthesis via DAP
CC pathway; LL-2,6-diaminopimelate from (S)-tetrahydrodipicolinate
CC (succinylase route): step 3/3. {ECO:0000256|ARBA:ARBA00005130}.
CC -!- SIMILARITY: Belongs to the peptidase M20A family. ArgE subfamily.
CC {ECO:0000256|ARBA:ARBA00005691}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVU35244.1}.
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DR EMBL; SADE01000003; RVU35244.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437QL54; -.
DR OrthoDB; 9809784at2; -.
DR Proteomes; UP000287447; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0008777; F:acetylornithine deacetylase activity; IEA:UniProtKB-EC.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0006526; P:arginine biosynthetic process; IEA:UniProtKB-KW.
DR CDD; cd03894; M20_ArgE; 1.
DR Gene3D; 3.30.70.360; -; 1.
DR Gene3D; 3.40.630.10; Zn peptidases; 1.
DR InterPro; IPR010169; AcOrn-deacetyl.
DR InterPro; IPR001261; ArgE/DapE_CS.
DR InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR InterPro; IPR002933; Peptidase_M20.
DR InterPro; IPR011650; Peptidase_M20_dimer.
DR NCBIfam; TIGR01892; AcOrn-deacetyl; 1.
DR PANTHER; PTHR43808; ACETYLORNITHINE DEACETYLASE; 1.
DR PANTHER; PTHR43808:SF8; M20_DIMER DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF07687; M20_dimer; 1.
DR Pfam; PF01546; Peptidase_M20; 1.
DR SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
DR PROSITE; PS00759; ARGE_DAPE_CPG2_2; 1.
PE 3: Inferred from homology;
KW Amino-acid biosynthesis {ECO:0000256|ARBA:ARBA00022605};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000313|EMBL:RVU35244.1};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000287447};
KW Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT DOMAIN 170..273
FT /note="Peptidase M20 dimerisation"
FT /evidence="ECO:0000259|Pfam:PF07687"
SQ SEQUENCE 374 AA; 39892 MW; B7F05B7171921737 CRC64;
MTVEDILANL VGFQSVVGTP NGEIVEWIHT YCKAHGAETS VHIGPEGDRA NLFVTIGPRD
GHGYILSGHM DVVPANEPEW NSDPFTMRRE GERLYGRGTS DMKGFIACAL AALPRLSSMG
LKHPIHLALS YDEEAGARGV PHLIAELPKL CEQPRGAIIG EPSGMQAVRA HKGKAAARIE
VIGCPGHSSR PDLGRNAIHA MAEIVTGAVA YDLALAETPG DADFEPSYST LQIGTIAGGQ
AVNIIPDRCH AEIELRAVPG LSPTELLEPV KACALALRER GFDVDWQEMS TYPGLSLAKE
SDLAALLADL TGKEVRAAVS YGTEAGLFQA AGIDAVICGP GEIDRAHRPN EYVEIAELAD
CQRMIEELAR RLAA
//
