ID A0A437SUF2_9LACO Unreviewed; 453 AA.
AC A0A437SUF2;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=DEAD/DEAH box helicase {ECO:0000313|EMBL:RVU70559.1};
GN ORFNames=EJK17_07085 {ECO:0000313|EMBL:RVU70559.1};
OS Lactobacillus xujianguonis.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Lactobacillus.
OX NCBI_TaxID=2495899 {ECO:0000313|EMBL:RVU70559.1, ECO:0000313|Proteomes:UP000288291};
RN [1] {ECO:0000313|EMBL:RVU70559.1, ECO:0000313|Proteomes:UP000288291}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HT111-2 {ECO:0000313|EMBL:RVU70559.1,
RC ECO:0000313|Proteomes:UP000288291};
RA Meng J.;
RL Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVU70559.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; RXIA01000017; RVU70559.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A437SUF2; -.
DR Proteomes; UP000288291; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd00268; DEADc; 1.
DR CDD; cd18787; SF2_C_DEAD; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR014014; RNA_helicase_DEAD_Q_motif.
DR PANTHER; PTHR47959:SF13; ATP-DEPENDENT RNA HELICASE RHLE; 1.
DR PANTHER; PTHR47959; ATP-DEPENDENT RNA HELICASE RHLE-RELATED; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
DR PROSITE; PS51195; Q_MOTIF; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Helicase {ECO:0000256|ARBA:ARBA00022806, ECO:0000313|EMBL:RVU70559.1};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000288291}.
FT DOMAIN 3..31
FT /note="DEAD-box RNA helicase Q"
FT /evidence="ECO:0000259|PROSITE:PS51195"
FT DOMAIN 34..207
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 234..377
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 410..453
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 3..31
FT /note="Q motif"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00552"
FT COMPBIAS 418..432
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 433..453
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 453 AA; 51737 MW; 015B0487A9D7A069 CRC64;
MNNTFTDSRI RPELQTGLEK IHFDKPTEVQ ERVIPALLSR VNVVVQAATG SGKTHAYLVP
VFNDIDETKN YVQAIITAPS RELADQLYQV AKQLRKASGL DISIGHLAGG TDRERQLAKM
ANKKPQLVIA TPGRLLDFVE KKVFAVDSVK DFIIDEADMT LDMGFLADID KVAAKLPKDV
LFAAFSATIP VKLANFLRKY MAHPDEIIID NPAVIAPTIK NDLLDIGSKD RKNVLYKLLT
LGQPYLALVF ANTKQKVDEL VNFLQDQGLK VAKIHGGITE RERKRTLRQV EQGQFQYVVA
SDLAARGLDI DGVSLVINYE VPRDLEFVIH RIGRTGRNGL PGHAITLIRE EEMKRIQELE
NMGVHFDFVE LKHGELVPRK HYRSRENRQG KNRKLDTKLV GYVKKEKRIR KPGYKKKIKR
AIQEDNRQKR KLEQRHEIRK AKRLRKRKRE QGR
//
