ID A0A438ATS5_9NOCA Unreviewed; 746 AA.
AC A0A438ATS5;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 14.
DE RecName: Full=SSD domain-containing protein {ECO:0000259|PROSITE:PS50156};
GN ORFNames=EGT50_10595 {ECO:0000313|EMBL:RVW02183.1};
OS Rhodococcus xishaensis.
OC Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC Rhodococcus.
OX NCBI_TaxID=2487364 {ECO:0000313|EMBL:RVW02183.1, ECO:0000313|Proteomes:UP000283479};
RN [1] {ECO:0000313|EMBL:RVW02183.1, ECO:0000313|Proteomes:UP000283479}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LHW51113 {ECO:0000313|EMBL:RVW02183.1,
RC ECO:0000313|Proteomes:UP000283479};
RA Li L., Lin H.W.;
RT "Rhodococcus spongicola sp. nov. and Rhodococcus xishaensis sp. nov. from
RT marine sponges.";
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the resistance-nodulation-cell division (RND)
CC (TC 2.A.6) family. MmpL subfamily. {ECO:0000256|ARBA:ARBA00010157}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVW02183.1}.
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DR EMBL; RKLO01000004; RVW02183.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A438ATS5; -.
DR OrthoDB; 2365435at2; -.
DR Proteomes; UP000283479; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR InterPro; IPR004869; MMPL_dom.
DR InterPro; IPR000731; SSD.
DR PANTHER; PTHR33406; MEMBRANE PROTEIN MJ1562-RELATED; 1.
DR PANTHER; PTHR33406:SF6; MEMBRANE PROTEIN SCO0839-RELATED; 1.
DR Pfam; PF03176; MMPL; 2.
DR SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR PROSITE; PS50156; SSD; 2.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000283479};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 21..40
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 194..212
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..240
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 252..274
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 295..316
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 328..355
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 392..411
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 574..591
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 598..622
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 634..651
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 672..694
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 700..723
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 219..349
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
FT DOMAIN 601..729
FT /note="SSD"
FT /evidence="ECO:0000259|PROSITE:PS50156"
SQ SEQUENCE 746 AA; 78472 MW; 34B7C9593941D9DB CRC64;
MTRVQSTGGT SPGTAGSSRR GWPVFTAVAF AIAALIFGGL GGSFQGKLAE VQKNDNASYL
PSSSESTIVA NESAKFLEVE TIPGVVVFHR DGGLTDADKD AIEQARISMA SIEGVDTDGV
TPTQFSSDDT TASVFVPLIA EENGTTVVGP DLVSVEQEVL DAARNAVATD LEVLPAGPGG
LLAALIDAFE GLDSTLLVVA LSVVILILLV VYRSPVLWFF PLFSALLALG VASMLVYLLA
DNEILTLTGQ SQGIMFVLVI GAGTDYALLL ISRYREELHF YENRFDAMIK AWRESAPAIT
ASAATVILGL LCLSFSELNS NKSMGPVAAI GIACTYLVMM SFLPVALSAA GRWVFWPRKP
KANHAEDSAT DMVTHRLWSR IAEVVGRRDR PAWIGATALL AVLFAVGIGS LQTDGLTSTE
FFTTKPDAVR GQELYDAKFD RGAGAPAVIT ANASSVDAVI EAASGVEGVN QSPGSVCVQV
DEAKVRALLQ GLGPGAPQQL PPGCPPAALN VDPIDGRTMI NADLADSYDS PEALQTVQRL
RDTLHALPGA DALVGGTSAA TLDVQIASVH DRNLIIPIVL VVIFVVLALL LRALLIPVIL
IATVVLSFAA ALGVSGLFFT YVFNFPGADQ SFPLYAFVFL VALGIDYNIF LMTRVREETQ
THGTRAGVLR GLTVTGGVIT SAGIVLAATF GVLGVLPLVF LAQIGFAVAF GVLLDTIVVR
SVLVPALSHD IGKPIWWPSR LARARD
//
