ID A0A438MC37_9ACTN Unreviewed; 1289 AA.
AC A0A438MC37;
DT 08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT 08-MAY-2019, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=ATP-dependent helicase HrpA {ECO:0000313|EMBL:RVX43276.1};
GN ORFNames=EDD27_5951 {ECO:0000313|EMBL:RVX43276.1};
OS Nonomuraea polychroma.
OC Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
OC Streptosporangiaceae; Nonomuraea.
OX NCBI_TaxID=46176 {ECO:0000313|EMBL:RVX43276.1, ECO:0000313|Proteomes:UP000284824};
RN [1] {ECO:0000313|EMBL:RVX43276.1, ECO:0000313|Proteomes:UP000284824}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 43925 {ECO:0000313|EMBL:RVX43276.1,
RC ECO:0000313|Proteomes:UP000284824};
RA Klenk H.-P.;
RT "Sequencing the genomes of 1000 actinobacteria strains.";
RL Submitted (JAN-2019) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:RVX43276.1}.
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DR EMBL; SAUN01000001; RVX43276.1; -; Genomic_DNA.
DR OrthoDB; 9805617at2; -.
DR Proteomes; UP000284824; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR GO; GO:0003724; F:RNA helicase activity; IEA:InterPro.
DR CDD; cd17989; DEXHc_HrpA; 1.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR024590; HrpA_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR010222; RNA_helicase_HrpA.
DR NCBIfam; TIGR01967; DEAH_box_HrpA; 1.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF83; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE DHX16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF11898; DUF3418; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00382; AAA; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Helicase {ECO:0000313|EMBL:RVX43276.1};
KW Hydrolase {ECO:0000313|EMBL:RVX43276.1};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000284824}.
FT DOMAIN 88..251
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 269..440
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT COILED 760..787
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 1289 AA; 146700 MW; A8AAC1B6F448B36C CRC64;
MGTSSLSSPL AELQSRLPEL MPRDQRRLRR RLDGMRRVRS RDTRDKIVAE ILADVERAEQ
RLARRREAVP QVRYPENLPV SQRKDDILEA IRDHQIVIIA GETGSGKTTQ IPKICLELGR
GVRGLIGHTQ PRRIAARTVA ERIAEELGTE LGEVVGYKVR FTDQASDRTL VKLMTDGILL
AELQNDRLLD QYDTLIIDEA HERSLNIDFI LGYLKQLLPK RPDLKVVITS ATIDPERFSR
HFGDAPIIEV SGRTYPVEVR YRPLDEDDDQ TQGIVNACQE LVTEGPGDIL VFLSGEREIR
DAADALTKAD FRNTEILPLY ARLSAAEQHR VFQRHTGRRI VLATNVAETS LTVPGIKYVV
DPGYARISRY SHRTKVQRLP IEPISQASAN QRKGRSGRTS DGICIRLYEE EDFLSRPEFT
DPEILRTNLA SVILQMTSIG LGDIEAFPFV EPPDRRQVKD GVNLLHELGA FDVHGKLTPI
GRKLANLPVD PRLGRMVLEA EKNGCLREVM VIAAALSIQD PRERPADKQQ QADEKHRRFA
DPDSDFLAYL NLWNYLRDKQ KELSSSAFRR LCKAEFLNYL RVREWQDIYS QLRQSLGAQP
NSAPADPQHV HASLLVGLLS HIGVKDVMEK RGADGRRPIQ EYIGARNARF AIFPGSTLAK
KQPQWVMSAE LVETSRLWAR VNAKIEPDWV EPLAQHLVKR TYSEPHWEKN QGAVIALEKV
TLYGVPLVVG RKVNYGRIDP DLSRELFIRH ALVEGDWDTH HRFLKENRKL LEEVEELENR
ARRRDILVDD EALFDFYDQR VPADVVSARH FDSWWKKAGR ETPELLTFSP EMLVNEGADI
SARDYPDTWK QLGQRMKLTY QFEPGADADG VTVHVPLQVL NQVSSDGFDW QIPGLREELI
TALIRSLPKH LRRNFVPAPN YAKQVLAGVR QGGEPLLAAV ERELLRLTGV RVPREAWQLD
QVPDHLRITY RVIDERRRTV AEDKDLDALK RRLAPKLRQT LSQAGDDLEQ TGLHTWSFGR
LPKVFEQGRM KGYPALVDAG DSVSIKIYET EAEQRRSHWP GVRRLLLLNV TNPAKSLLGG
LSNQAKLALS RSPHGGAVAL FDDVVNAAVD KLMLDVGGPA WDPVGFDRLY QHVRAHLHDT
AADVLGKVEQ ILAVWHEAGA RLDALRPSAS TDDIRDQLSK LVYPGFVTAT GYRRLSDILR
YIRAIDRRLT KLPEEPWRDQ EWMDRVHKVE DDYHDLLEKL HPARRGDPDV VEIRWMIEEL
RVSFFAQTLG TPTPVSEKRI AKTMEKLTP
//
