ID   A0A439CZA3_9PEZI        Unreviewed;       861 AA.
AC   A0A439CZA3;
DT   08-MAY-2019, integrated into UniProtKB/TrEMBL.
DT   08-MAY-2019, sequence version 1.
DT   22-FEB-2023, entry version 10.
DE   RecName: Full=V-type proton ATPase subunit a {ECO:0000256|RuleBase:RU361189};
GN   ORFNames=EKO27_g7564 {ECO:0000313|EMBL:RWA07535.1};
OS   Xylaria grammica.
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Sordariomycetes;
OC   Xylariomycetidae; Xylariales; Xylariaceae; Xylaria.
OX   NCBI_TaxID=363999 {ECO:0000313|EMBL:RWA07535.1, ECO:0000313|Proteomes:UP000286045};
RN   [1] {ECO:0000313|EMBL:RWA07535.1, ECO:0000313|Proteomes:UP000286045}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IHI A82 {ECO:0000313|EMBL:RWA07535.1,
RC   ECO:0000313|Proteomes:UP000286045};
RA   Buettner E., Kellner H.;
RT   "Draft genome sequence of Xylaria grammica IHI A82.";
RL   Submitted (DEC-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Essential component of the vacuolar proton pump (V-ATPase), a
CC       multimeric enzyme that catalyzes the translocation of protons across
CC       the membranes. Required for assembly and activity of the V-ATPase.
CC       {ECO:0000256|RuleBase:RU361189}.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the V-ATPase 116 kDa subunit family.
CC       {ECO:0000256|ARBA:ARBA00009904, ECO:0000256|RuleBase:RU361189}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:RWA07535.1}.
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DR   EMBL; RYZI01000252; RWA07535.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A439CZA3; -.
DR   STRING; 363999.A0A439CZA3; -.
DR   Proteomes; UP000286045; Unassembled WGS sequence.
DR   GO; GO:0000220; C:vacuolar proton-transporting V-type ATPase, V0 domain; IEA:InterPro.
DR   GO; GO:0046961; F:proton-transporting ATPase activity, rotational mechanism; IEA:InterPro.
DR   InterPro; IPR002490; V-ATPase_116kDa_su.
DR   InterPro; IPR026028; V-type_ATPase_116kDa_su_euka.
DR   PANTHER; PTHR11629:SF63; V-TYPE PROTON ATPASE SUBUNIT A; 1.
DR   PANTHER; PTHR11629; VACUOLAR PROTON ATPASES; 1.
DR   Pfam; PF01496; V_ATPase_I; 1.
DR   PIRSF; PIRSF001293; ATP6V0A1; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Hydrogen ion transport {ECO:0000256|ARBA:ARBA00022781,
KW   ECO:0000256|RuleBase:RU361189};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065,
KW   ECO:0000256|RuleBase:RU361189};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361189};
KW   Reference proteome {ECO:0000313|Proteomes:UP000286045};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|RuleBase:RU361189};
KW   Transport {ECO:0000256|ARBA:ARBA00022448, ECO:0000256|RuleBase:RU361189}.
FT   TRANSMEM        422..446
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        458..483
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        547..565
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        577..602
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        643..664
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   TRANSMEM        787..812
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|RuleBase:RU361189"
FT   COILED          101..128
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          279..306
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   861 AA;  98089 MW;  7987325D4A229EFB CRC64;
     MAPSKQSMFR SADMSMVQLY ISNEIGRECV TALGELGLVQ FRDLNGDVSA FQRTFTQEIR
     RLDNVERQLR YFHAQMEKAS IPLRKLDLDV ETLAPPTTSE IDELAERGQG LEQRIAQLND
     SYETLKKREV ELTEWRWVLR EAGGFFDRAH GSVDEIRVST EDDDAPLLQD VEQHNQAGDV
     ERSFSGMNIG FVAGVINRER VAAFERILWR TLRGNLYMNQ SEIPEPLIDP TNNEAIRKNV
     FVIFAHGKEI LAKIRKISES MGAEIYNVDE NTDLRRDQMH EVNARLNDVQ NVLQNTQQTL
     EAELTQIGQS LAAWMVLVTK EKATYKTLNL FSFDRQRRTL IAEGWCPTTD LPRIRSTLQD
     VTNRAGLSVP SIINEIKTSK TPPTYLRTNK FTEAFQTIIN AYGTTTYQEV NPALPAIVTF
     PFLFAVMFGD FGHAVIMLAA ALAMIYWERP LKKVTFELFA MIYYGRYIAL VMAVFSLFTG
     LVYNDVFSKS LTLFDSAWEW DVPEGWKEGQ PLVATLKDDY RYPFGLDWMW HGTDNDLLFT
     NSYKMKMSII LGWAHMTYSL CLAYVNAKHF KKPIDIWGNF VPGMIFFQAI FGYLVVCIIY
     KWSVDWYAVG RSPPGLLNML IYMFLQPGTI DEELYSGQAK VQITLLLLAF VQVPILLFLK
     PFYLRWEHLK TRAKGYRGIG EHSRVSALDD DEDGHHAGNG NGRFSIETDD GEGVTMIAHG
     GDDEDGHEEF EFSEVMIHQV IHTIEFCLNC VSHTASYLRL WALSLAHQQL SSVLWDMTLG
     PTLTKTGVLG VIMIFLAFGL WFSLTCAILI AMEGCSAMLH SLRLQWVEAQ SKYAEFAGHM
     FAPFSFITML EEDEGLAEFT G
//